Pharmacovigilance study of the association between progestogen and depression based on the FDA adverse event reporting System (FAERS) [PDF]
Progestogens commonly used in the clinic include levonorgestrel, etonogestrel, medroxyprogesterone, hydroxyprogesterone, progesterone, desogestrel, and megestrol.
Hui Gao, Xiaohan Zhai, Yan Hu, Hang Wu
doaj +2 more sources
A case report and literature review: A 19‐year‐old with endometrial carcinoma treated with medroxyprogesterone acetate. Importance of the medical interview and endometrial examination [PDF]
Key Clinical Message A 19‐year‐old woman had stage IA endometrial carcinoma treated with medroxyprogesterone acetate and experienced a recurrence. This patient's experience illustrates the importance of a thorough history and endometrial assessment in ...
Shinichiro Katsuma +4 more
doaj +2 more sources
The value of diffusion-weighted imaging and semi-quantitative dynamic contrast-enhanced MRI in predicting the efficacy of medroxyprogesterone acetate treatment for atypical endometrial hyperplasia and endometrial carcinoma [PDF]
Background It will be important to noninvasively evaluate the efficacy of treatment for patients with atypical endometrial hyperplasia (AEH) and endometrial carcinoma (EC) who wish to have children. The study aimed to explore the feasibility of diffusion-
Mingming Liu +5 more
doaj +2 more sources
ObjectiveTo compare the clinical outcomes of dydrogesterone (DYG) and medroxyprogesterone (MPA) in the progestin-primed ovarian stimulation (PPOS) protocol for patients with poor ovarian response (POR).Patients and MethodsThis was a retrospective cohort ...
Junwei Zhang +6 more
doaj +1 more source
Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]
Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna +8 more
core +2 more sources
The protective effect of medroxyprogesterone acetate on propionic acid-induced autism in rats was evaluated. For this purpose, 30 rats were divided into three groups.
Mehmet Fatih Bozkurt +4 more
doaj +1 more source
Progestogens Are Metabolized by the Gut Microbiota: Implications for Colonic Drug Delivery
Following oral administration, the bioavailability of progestogens is very low and highly variable, in part due to metabolism by cytochrome P450 enzymes found in the mucosa of the small intestine.
Zoe Coombes +6 more
doaj +1 more source
Background and objectives: Abnormal uterine bleeding is a significant clinical and gynaecological concern that necessitates its safe and effective treatment.
Suhail Ahmad Mir +11 more
doaj +1 more source
Characteristics of endometrial cancer progressed to extrauterine lesions following fertility preserving medroxyprogesterone acetate therapy for young endometrial cancer patients. [PDF]
Kitazawa S +7 more
europepmc +3 more sources
Use of depot medroxyprogesterone acetate and fracture risk [PDF]
Depot medroxyprogesterone acetate (DMPA), which has a high rate of use among teenagers in Europe and the United States, has been associated with impaired bone mineral acquisition during adolescence and accelerated bone loss in later life.
Brauchli, Yolanda B. +4 more
core +1 more source

