Results 111 to 120 of about 48,009 (234)

Vandetanib (ZD6474) in the Treatment of Medullary Thyroid Cancer

Clinical Medicine Insights: Oncology, 2011
Vandetanib (ZD6474) is an orally bioavailable small molecule tyrosine kinase inhibitor of multiple growth factor receptors, including RET (Rearrange during transfection), vascular endothelial growth factor receptor-2 (VEGFR-2) and epidermal growth factor
Hari Deshpande, Sanziana Roman, Jaykumar Thumar, Julie Ann Sosa   +3 more
doaj   +1 more source

Segmental Tracheal Resection for Thyroid Cancer: Perioperative Morbidity, Locoregional Control, and Survival

Head &Neck, Volume 48, Issue 3, Page 644-649, March 2026.
ABSTRACT Background Segmental tracheal resection is rarely needed for advanced thyroid cancer but is among the most complex, high‐risk thyroid surgeries. Methods Retrospective study of patients undergoing segmental tracheal resection for thyroid cancer at MD Anderson Cancer Center (2005–2024).
Anastasios Maniakas, David C. Wilde, Isabelle Fournier, Emily K. Hyde, Li Xu, Jennifer R. Wang, Neil D. Gross, Erich M. Sturgis, Victoria Banuchi, Naifa L. Busaidy, Maria E. Cabanillas, Priyanka Iyer, Ramona Dadu, Steven G. Waguespack, Mimi I. Hu, G. Brandon Gunn, Michael Kwon, Salmaan Ahmed, Michelle D. Williams, Mark E. Zafereo   +19 more
wiley   +1 more source

Research progress on the immune microenvironment and immunotherapy of thyroid cancer [PDF]

Waike lilun yu shijian
Thyroid cancer is the most common endocrine malignancy. Although most patients achieve good prognosis through surgery and conventional treatments, approximately 15%-20% of patients with papillary thyroid cancer and the anaplastic and medullary thyroid ...
LIAO Zhenyu, ZHU Wenxin, YAN Jiqi
doaj   +1 more source

Biological functions of CDK5 and potential CDK5 targeted clinical treatments. [PDF]

, 2017
Cyclin dependent kinases are proline-directed serine/threonine protein kinases that are traditionally activated upon association with a regulatory subunit.
Casimiro, Mathew C., Pestell, Richard G., Shupp, Alison   +2 more
core   +2 more sources

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu, Rou Xue, Xiangwen Luo, Jiangnan Liao, Zongbo Zhang, Jinhai Deng, Teng Liu, Xin Li, Zhe‐Sheng Chen, Mingzhu Yin   +9 more
wiley   +1 more source

Medullary Thyroid Carcinoma with Micronodular Lung Metastases: A Case Report with an Emphasis on the Imaging Findings

Case Reports in Medicine, 2010
Medullary thyroid carcinoma is a rare malignancy that arises from calcitonin-producing C-cells and frequently metastasizes to lymph nodes in the neck. Distant metastases may involve bone, lung, and liver.
Nina Ventura, Edson Marchiori, Gláucia Zanetti, Antonio Muccillo, Mariana Leite Pereira, Guilherme Abdalla, Pedro Martins, Carolina Lamas Constantino, Rodrigo Canellas, Viviane Brandão, Romulo Varella de Oliveira   +10 more
doaj   +1 more source

Melanotic medullary carcinoma of thyroid – report of a rare case with brief review of literature [PDF]

, 2008
Background Melanin production in medullary carcinoma is extremely uncommon. Case presentation We report a rare variant of medullary carcinoma of thyroid with melanin production in a 52-year-old woman who presented with swelling in the thyroid of 3 months
Kamaljeet Singh, Mehar C Sharma, Deepali Jain, Rajinder Kumar   +3 more
core   +2 more sources

Efficacy and Safety of Tirzepatide in Japanese Participants With Obesity: A Subpopulation Analysis of the SURMOUNT‐1 Trial

Obesity, Volume 34, Issue 3, Page 608-621, March 2026.
ABSTRACT Objective This prespecified subpopulation analysis aimed to assess the efficacy and safety of once‐weekly tirzepatide versus placebo alongside lifestyle intervention in Japanese adults with obesity or overweight. Methods Data from 102 Japanese adults in the SURMOUNT‐1 trial with BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 and ≥ 1 weight‐related comorbidity ...
Yasushi Ishigaki, Masamichi Yamada, Tomotaka Shingaki, Tomonori Oura, Iichiro Shimomura   +4 more
wiley   +1 more source

Society for Maternal‐Fetal Medicine Consult Series #76: Cancer in pregnancy

Pregnancy, Volume 2, Issue 2, March 2026.
Abstract Approximately one in 1000 pregnancies is complicated by the diagnosis of cancer each year, and the incidence of cancer among reproductive‐age individuals is increasing. Management of a pregnant person with cancer can be complex and warrants a multidisciplinary approach to care.
Society for Maternal‐Fetal Medicine (SMFM), Moti Gulersen, Clarissa Bonanno, Justin S. Brandt, Stephanie Pierce, Elyce H. Cardonick, SMFM Publications Committee   +6 more
wiley   +1 more source

Thyroid carcinoma in Pakistan: a retrospective review of 998 cases from an academic referral center

Hematology/Oncology and Stem Cell Therapy, 2009
BACKGROUND AND OBJECTIVES: To address the need for epidemiologic data on thyroid carcinoma in Pakistan, we evaluated the frequency and types of thyroid carcinoma with respect to age and sex.
Uzma Bukhari, Saleem Sadiq, Jawaid Memon, Farooq Baig   +3 more
doaj   +1 more source