Results 91 to 100 of about 6,236 (217)

MEFV Mutations Modify the Clinical Presentation of Henoch-Schonlein Purpura

, 2008
Objective. To investigate the prevalence of MEFV gene mutations in Turkish patients with Henoch-Schonlein purpura (HSP) but with no symptoms of familial Mediterranean fever (FMF).
Arisoy, Nil, Yalcinkaya, Fatos, Acar, Banu, Uguten, Deniz, Ekim, Mesiha, Kasapcopur, Oezguer, Kara, Nazli, Ozcakar, Z. Birsin, Cakar, Nilguen, Soy, Derya, Uncu, Nermin   +10 more
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The influence of carrying MEFV gene variants on juvenile systemic lupus erythematosus

, 2021
© 2019, Springer-Verlag GmbH Germany, part of Springer Nature.Juvenile-onset systemic lupus erythematosus (jSLE) patients typically have a more severe disease course than adults with SLE.
Ayaz, Nuray Aktay, Sözeri, B, Sözeri, Betül, Karadağ, Şerife Gül, Kısaarslan, AP, Ayaz, Nuray, Çakan, Mustafa, Çakan, M, Tanatar, Ayşe, Kısaarslan, Ayşenur, Karadağ, ŞG   +10 more
core   +1 more source

Decreased MEFV gene expression in rheumatoid arthritis patients

Genetics and Molecular Research, 2015
Rheumatoid arthritis (RA) is a major cause of adult chronic inflammatory arthritis and an autoimmune disease of unknown etiology in which the inflammatory pathology involves T cell activation. Genetic mutations in the Mediterranean fever (MEFV) gene, encoding pyrin, influence the severity of RA, but the underlying mechanisms are not completely ...
E O, Etem, S S, Koca, D, Erol, S, Yolbas, E, Oz, H, Elyas, A, Isık   +6 more
openaire   +2 more sources

In Vivo Methylation Studies Of Mefv Gene

, 2008
Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2008Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2008MEFV geni ilk olarak serozal iltihaplanma ve karın ağrısı ile ilerleyen Ailevi ...
Karaca, Esra
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A molecular analysis of familial Mediterranean fever disease in a cohort of Turkish patients

Annals of Saudi Medicine, 2012
BACKGROUND AND OBJECTIVES: Familial Mediterranean fever (FMF) is an autosomal recessive disorder caused by mutations in MEFV gene, which encodes pyrin. FMF is especially prevalent among Turks, Armenians, non-Ashkenazi Jews, and Arabs.
Munis Dundar, Aslihan Kiraz, Elif Funda Emirogullari, Çetin Saatci, Serpil Taheri, Mevlut Baskol, Seher Polat, Yusuf Özkul   +7 more
doaj   +1 more source

Cost-saving approach with screening of selected variants in genetic diagnosis in Turkish pediatric familial Mediterranean fever patients: a single center longitudinal study

The Turkish Journal of Pediatrics
Background. The aim of this study was to investigate whether a short exon screening consisting of selected variants could confirm the diagnosis in patients with a preliminary diagnosis of familial Mediterranean fever (FMF), thus providing a cost-saving ...
Betül Sözeri, Şengül Çağlayan, Taner Coşkuner, Yasemin Kendir-Demirkol   +3 more
doaj   +1 more source

A novel single variant in the MEFV gene causing Mediterranean fever and Behçet’s disease: a case report

Journal of Medical Case Reports, 2018
Background Familial Mediterranean fever is an autoinflammatory disease of unknown etiology, characterized clinically by recurrent attacks of sudden-onset fever with arthralgia and/or thoracoabdominal pain and pathogenetically by autosomal recessive ...
Maria Zerkaoui, Fatima Zahra Laarabi, Yousra Ajhoun, Bouchra Chkirate, Abdelaziz Sefiani   +4 more
doaj   +1 more source

MEFV gene variation R202Q is associated with metabolic syndrome

, 2016
OBJECTIVE: MEFV (Mediterranean fever) gene encoding pyrin regulates inflammatory responses. It has been shown that MEFV gene variations are associated with higher acute phase responses and altered course in the different inflammatory diseases.
Akyol, M., Çobankara, Veli, Balkarli, A., Elmas, Levent, Tepeli, Emre   +4 more
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Loss of Mefv does not affect the response to LPS.

, 2013
A, Relative expression of Mefv in bone marrow-derived macrophages (BMMΦ), resting peritoneal macrophages (rpMΦ), and elicited peritoneal macrophages (pMΦ) from WT mice was detected by real-time PCR. n ≥3 mice per cell type. Data are expressed as relative
MyTrang Nguyen (296629), Beverly H. Koller (296631), Martina Kovarova (296630), Jenny P.-Y. Ting (143357), Pamela R. Hesker (296628)   +4 more
core   +1 more source

Gutlu hastalarda mefv gen mutasyon sıklığı ve klinik bulgularla ilişkisi

, 2013
Gut artmış serum ürik asit düzeyi ile beraber monosodyum ürat kristallerine karşı gelişen inflamatuar yanıtın yol açtığı hastalıkdır. Gut patogenezinde rol oynayan en önemli inflamatuar sitokin IL-1??dır.
Balkarlı, Ayşe
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