Results 91 to 100 of about 21,749 (244)
Platelets and megakaryocytes in cancer
Journal of Thrombosis and HaemostasisPlatelets have important roles in hemostasis but also actively participate in cancer metastasis and inflammatory processes. They are produced by large precursor cells, the megakaryocytes, residing mainly in the bone marrow. Clinically, elevated platelet counts and/or increased platelet-to-lymphocyte ratio are being explored as biomarkers of metastatic ...
openaire +2 more sources
Case Report: T‐Lymphoblastic Leukemia in a Dog With Erythrophagia
Veterinary Clinical Pathology, EarlyView.ABSTRACT A 2‐year‐old male German Shepherd dog was presented with progressive weight loss, lethargy, and hyporexia. Hematologic analysis revealed a moderate macrocytic normochromic anemia and moderate thrombocytopenia. Additionally, a pronounced leukocytosis was observed, characterized by 33% large lymphoid cells, marked neutrophilia with a significant
Francisca B. Lang +7 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Persistent Immune Thrombocytopenia as a Post‐Acute Sequelae of COVID‐19: A Case Report
Public Health Challenges, Volume 5, Issue 4, December 2026.ABSTRACT Immune thrombocytopenia (ITP) is a recognized hematologic complication associated with coronavirus disease 2019 (COVID‐19), but its persistence years after acute infection remains uncommon. We present a case of a 52‐year‐old male who was diagnosed with COVID‐19 in June 2020. Following recovery from the acute illness, he had persistent fatigue,
Riazullah +5 more
wiley +1 more source
Quantitative Biology, Volume 14, Issue 4, December 2026.Abstract Single‐cell RNA sequencing (scRNA‐seq) generates high‐dimensional transcriptomic data but is severely affected by dropout events, which obscure true gene–gene relationships. These missing values introduce bias into downstream analyses, complicate data processing, and reduce analytical efficiency.
Shuang Xu +3 more
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.
Fatma AlBulushi, Eric McGinnis
wiley +1 more source
American Journal of Hematology, Volume 101, Issue 11, Page 2836-2852, November 2026.ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas +4 more
wiley +1 more source
Acquired Elliptocytosis With Hemolytic Anemia in Myelodysplastic Neoplasm With del(20q)
International Journal of Laboratory Hematology, EarlyView.
Nina Sicard +4 more
wiley +1 more source
Journal of Applied Toxicology, Volume 46, Issue 11, Page 3973-3988, November 2026.ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos +10 more
wiley +1 more source
Danthron as a novel IL-6R agonist promotes thrombopoiesis via the SRC/RAS/MAPK pathway
Frontiers in ImmunologyBackgroundThis study aimed to investigate the effects of danthron on promoting megakaryocyte (MK) differentiation and alleviating thrombocytopenia, as well as to elucidate its underlying mechanisms.MethodsCell proliferation and apoptosis of Meg-01 and ...
Rui Liao +13 more
doaj +1 more source