Results 71 to 80 of about 24,025 (269)
Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potential
Nature CommunicationsRed blood cells and platelets derive from bi-potential bone marrow megakaryocyte-erythroid progenitors, but their study is constrained by cell scarcity and limited experimental systems.
Ruiqiong Wu +14 more
doaj +1 more source
Food Chemistry International, EarlyView.Sanguinarine, a toxic alkaloid present in argemone, can lead to epidemic dropsy or chronic diseases through DNA intercalation and immune system suppression. Regulatory efforts face challenges due to economic motivations for adulteration as well as technical, social, and infrastructure barriers.
Gururaj Pejavara Narayana +4 more
wiley +1 more source
iMeta, EarlyView.This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou +8 more
wiley +1 more source
Changes in megakaryopoiesis over ontogeny and their implications in health and disease
Platelets, 2020 A growing body of research has made it increasingly clear that there are substantial biological differences between fetal/neonatal and adult megakaryopoiesis.
Patricia Davenport +2 more
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Matrix Mechanosensation in the Erythroid and Megakaryocytic Lineages
Cells, 2020 The biomechanical properties of the bone marrow microenvironment emerge from a combination of interactions between various extracellular matrix (ECM) structural proteins and soluble factors.
Christina M. Ward, Katya Ravid
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, 2007 Scheme electron microscopy. The megakaryocyte is derived from a pro-megakaryocyte which originates from splenic stem cells (CFU-S, colony forming units-spleen).
Poels, Lambert G.
core
Interdisciplinary Medicine, EarlyView.Extracellular vesicles play pivotal roles in both healthy hematopoiesis and hematologic malignancies. They not only regulate hematopoietic stem cell fitness but also drive cancer progression and drug resistance. Their clinical potential spans from serving as non‐invasive biomarkers to acting as innovative therapeutic platforms and drug delivery ...
Fengyu Chen +5 more
wiley +1 more source
In vitro culture of murine megakaryocytes from fetal liver-derived hematopoietic stem cells
Platelets, 2018 Megakaryocytes (MKs) are specialized precursor cells committed to producing and proliferating platelets. In a cytoskeletal-driven process, mature MKs generate platelets by releasing thin cytoplasmic extensions, named proplatelets, into the sinusoids. Due
Prakrith Vijey +2 more
doaj +1 more source
N-Methyl-D-Aspartate Receptors in Hematopoietic Cells: What Have We Learned?
Frontiers in Physiology, 2020 The N-methyl-D-aspartate receptor (NMDAR) provides a pathway for glutamate-mediated inter-cellular communication, best known for its role in the brain but with multiple examples of functionality in non-neuronal cells.
Maggie L. Kalev-Zylinska +6 more
doaj +1 more source
iRADIOLOGY, EarlyView.For patients with diffuse component, the presence of bulky disease and spleen involvement is strongly predictive of BMB‐confirmed BMI. Conversely, the absence of PET/CT‐detected BMI, bulky disease, and splenic involvement suggests a low likelihood of BMB‐confirmed BMI.
Haoying Huang +7 more
wiley +1 more source