Results 151 to 160 of about 133,463 (299)

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak, Reinhard Dummer, Egle Ramelyte   +2 more
wiley   +1 more source

MEK inhibitors in NF1-associated high-grade glioma: partial responses and outcomes from a single-institution cohort and literature review. [PDF]

J Neurooncol
Yu MC, Hsi AH, Adnan A, Knight SR, McCutcheon IE, Slopis JM, Kamiya-Matsuoka C.   +6 more
europepmc   +1 more source

Uintah High School Auto Mek Club

, 1939
Uintah High School boys participate in the Auto Mek Club. The club helps further the mechanical skills of the members.

core  

MEK Inhibitor Associated Airway Injury in an Infant With Noonan Syndrome: A Case Report

The Laryngoscope, EarlyView.
An infant with Noonan syndrome treated with trametinib developed extensive mucosal sloughing of the upper and lower airway, followed by severe supraglottic scarring. Clinicians should consider airway toxicity as a potential adverse effect of MEK inhibitor therapy.
Veronica Drozdowski‐Nuccio, Rachel D. Yoon, Steven Tomasi, Dana M. Thompson, Inbal Hazkani   +4 more
wiley   +1 more source

MEK1/2 Signalling establishes an alloreactive effector T cell program through SMAD4 during cardiac allograft rejection. [PDF]

Clin Transl Med
Zhao J, Ran S, Zhou S, Li Y, Zhan W, Lai L, Cui J, Xia J, Wu J.   +8 more
europepmc   +1 more source

Chemically and Mechanically Recyclable Polyolefins Incorporating Covalent Adaptable Networks

Macromolecular Rapid Communications, EarlyView.
Low‐molecular‐weight polypropylene is converted into a crosslinked polyolefin containing a covalently adaptable network. The semicrystalline material remains melt‐processable and mechanically recyclable. Its thermal and mechanical properties are comparable to commercial polyolefins.
Andrii Tiiara, Bernadine Daichendt, Sergiy Minko, Olga Kuksenok, Igor Luzinov   +4 more
wiley   +1 more source

MEK/MAPK Inhibitors [PDF]

Journal of Thoracic Oncology, 2010
openaire   +2 more sources

Synthesis and Characterization of Monodisperse Sulfonic Acid‐Functionalized Hollow Polymer Microspheres Using Precipitation Polymerization as Recyclable Solid Acid Catalysts

Macromolecular Rapid Communications, EarlyView.
Monodisperse sulfonic acid‐functionalized hollow polymer microspheres were prepared via precipitation polymerization using a cleavable phenylsulfonate‐containing styrene dimer. Core‐shell particles were converted into hollow structures through selective core cleavage and functionalization.
Md Rabiul Alam, Yuri Hashimoto, Tomoya Ikke, Naoki Haraguchi   +3 more
wiley   +1 more source

Cobimetinib impairs tumor survival and immune escape by altering my-CAFs in BRAFV600E-mutated anaplastic thyroid carcinoma. [PDF]

Exp Hematol Oncol
Udinotti M, Ramm N, Hamdan TAAA, Khan MSA, Siebolts U, Bauer M, Lorenz K, Dierks C, Wickenhauser C, Seliger B.   +9 more
europepmc   +1 more source

All Simulation Data h5 Files meK-Means

All simulation h5 files for scMDC clustering analysis in meK-Means ...
Chari, Tara
core   +1 more source