Results 141 to 150 of about 133,463 (299)

All Simulation Data loom Files meK-Means

Simulated data loom files for benchmarking meK-Means ...
Chari, Tara
core   +1 more source

Exploring vaginal microbiota–tissue resident stem cell crosstalk: VCAM1/Akt signaling ‐mediated enhancement of regenerative capacity

Interdisciplinary Medicine, EarlyView.
Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim, Eun‐Kyung Min, Choon‐Mi Lee, Kun‐Hee Na, Chan Hum Park, YunJae Jung, Hwa‐Yong Lee   +6 more
wiley   +1 more source

Toll‐Like Receptors in the Mechanism of Hexabromocyclododecane‐Induced Production of Pro‐Inflammatory Cytokines

Journal of Applied Toxicology, EarlyView.
ABSTRACT Hexabromocyclododecane (HBCD), a brominated flame retardant, has raised increasing health concerns due to its bioaccumulation in human tissues and its ability to induce proinflammatory cytokines. Interleukin‐1β (IL‐1β), interleukin‐6 (IL‐6), and tumor necrosis factor‐α (TNF‐α) are major mediators of inflammation, and their chronic elevation ...
Wenjun Zhu, Aleshia Seaton‐Terry, Brian Townsend, Zinia Hunter, April Falconer‐Turner, Syeda Raika Shahid, Margaret Whalen   +6 more
wiley   +1 more source

Updated Benchmarking Datasets Looms meK-Means

Updated loom files for benchmarking datasets used in meK-Means ...
Chari, Tara
core   +1 more source

Diagnostic Lag in Precision Medicine

Clinical Pharmacology &Therapeutics, EarlyView.
Petr Heneberg
wiley   +1 more source

High‐Content Screening Comparison of 1R6F Cigarette Smoke Extract and Selected Heated Tobacco and Electronic Vapour Product Aerosol Extracts in Endothelial and Bronchial Epithelial Cell Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Cigarettes induce oxidative stress and DNA damage, processes that contribute to cardiovascular and pulmonary disease. High content screening (HCS) is an increasingly valuable tool for comparative toxicology because it enables simultaneous quantification of multiple mechanistic endpoints at single‐cell resolution. In this study, HCS was used to
Edgar Trelles Sticken, Konstantinos Papikinos, Fiona Chapman, Roman Wieczorek, Sarah Jean Pour, Torge Evenburg, Sandra Otte, Tiandan Wu, Liam Simms, Matthew Stevenson   +9 more
wiley   +1 more source

All Benchmark Data h5 Files meK-Means

Benchmark data h5 files for testing scMDC clustering for meK-Means ...
Chari, Tara
core   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

RAF isoform selectivity of MEK inhibitors and rational design of a covalent ARAF-MEK inhibitor. [PDF]

Sci Adv
Chakraborty S, Jiang J, Camallonga JV, Gazgalis D, Gero TW, Tavares MT, Dittemore G, Tkacik E, Beyett TS, Jang DM, Ha BH, Gottlieb FH, Levitz T, Metivier RJ, Schmoker AM, Scott DA, Jeon H, Jänne PA, Eck MJ.   +18 more
europepmc   +1 more source

MEK [PDF]

Chemical & Engineering News Archive, 1965
openaire   +1 more source