Results 121 to 130 of about 133,463 (299)

Scale‐Down Platforms for Process‐Oriented Enzyme Screening Using Microfluidics

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Enzyme screening platforms are typically evaluated based on their throughput and analytical performance rather than their ability to mimic the conditions encountered at large scale. In bioreactors, enzymes experience gradients in substrate concentration, oxygen availability, pH, temperature, and interfacial exposure, caused by imperfect mixing
Maria I. Rodriguez‐Torres   +5 more
wiley   +1 more source

TGF-beta coordinately activates TAK1/MEK/AKT/NFkB and SMAD pathways to promote osteoclast survival.

open access: yes, 2008
To better understand the roles of TGF-beta in bone metabolism, we investigated osteoclast survival in response TGF-beta and found that TGF-beta inhibited apoptosis. We examined the receptors involved in promotion of osteoclast survival and found that the
Ruan, Ming   +5 more
core   +1 more source

Nanoagonist‐mediated spatiotemporal reprogramming of macrophage phenotypes to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes the major molecular mechanisms governing TAM polarization and their coordinated interactions. It further highlights recent advances in nanoagonist‐based strategies that intervene in these pathways to reprogram TAMs, critically discussing their therapeutic potential, current limitations, and translational prospects.
Siqi Fang   +7 more
wiley   +1 more source

Behind the Mujahideen-e-Khalq (MeK)

open access: yes, 2003
Raids conducted by the Australian Federal Police (AFP) in June 2003 on the homes of Iranian Australians reportedly suspected of involvement with the Iranian opposition group, the MeK, have raised questions about the justification for such action ...
Nigel Brew   +1 more
core  

Environmental, Social and Governance (ESG) Drivers of Sustainability Transitions in Sub‐Saharan Africa: Why One Size Does Not Fit All

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Despite growing emphasis on sustainability transitions in developing economies, evidence remains limited on how environmental, social and governance (ESG) conditions shape sustainability outcomes in sub‐Saharan Africa (SSA). This study examines the environmental, social and governance drivers of sustainability transition performance across 39 ...
Emmanuel Kwaku Manu   +2 more
wiley   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

Mek Mulong: Kedah\u27s Unique Folk Performance

open access: yes, 2016
The essay considers a type of Malay folklore found in the state of Kedah, the mek mulong, which can be categorised as a folk performance. The authentic mek mulong still thrives in Kampung Baru Wang Tepus in Jitra.
Mohamad Luthfi Abdul Rahman
core  

Benchmarking and Simulation Raw SD Files meK-Means

open access: yes
sd files from Monod or meK-Means inference runs for meK-Means ...
Chari, Tara
core   +1 more source

Benchmarking and Simulation SD Files for meK-Means II

open access: yes
Benchmarking and simulation sd files from Monod and meK-Means for meK-Means ...
Chari, Tara
core   +1 more source

Xylose Acetals ‐ a New Class of Sustainable Solvents and Their Application in Enzymatic Polycondensation

open access: yesChemSusChem, Volume 18, Issue 6, March 15, 2025.
Novel organic solvents with an unmodified carbohydrate core were synthesised both from D‐xylose and directly from biomass and were successfully used as reaction media for lipase biocatalysts to synthesise aliphatic and aromatic polyesters. Abstract The use of organic solvents in academic research and industry applications is facing increasing ...
Anastasia O. Komarova   +8 more
wiley   +1 more source

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