Results 131 to 140 of about 133,463 (299)
Developmental Dynamics, EarlyView.Abstract Understanding the dynamic nature of developmental networks requires live imaging techniques capable of capturing real‐time developmental processes in wild‐type and mutant embryos as they are exposed to pharmacological perturbations. A peculiar developmental patterning process in early vertebrate embryos is the sequential segmentation of ...
Mohammed Nakhuda, M. Fethullah Simsek
wiley +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Epilepsia Open, EarlyView.Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Benchmarking Datasets for meK-Means
Benchmarking dataset (Allen Institute MOp data and scMixology cell line data) loom files for meK ...
Chari, Tara
core +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Approximately 6%–8% of children and adolescents with rhabdomyosarcoma (RMS) have an underlying cancer predisposition disorder (CPD), which varies between embryonal and alveolar subtypes and other clinical characteristics. Identifying a CPD remains challenging, as traditional approaches rely on clinical features and family history. Additionally,
Taylor M. Luckie +12 more
wiley +1 more source
Photocatalytic Oxidation of Methyl Ethyl Ketone in a Fluidized Bed Reactor
بهداشت و ایمنی کار, 2012 Introduction: Emission of volatile organic compounds through industrial processes to the environment has been received more attentions currently. Photocatalytic oxidation process as a new emerging technique in air purification can be substituted for ...
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International Journal of Cancer, EarlyView.ABSTRACT Biliary tract cancers (BTCs) are aggressive malignancies associated with a poor prognosis. Although molecular profiling is recommended to guide therapeutic decision‐making, real‐practice data on the prevalence and prognostic significance of genomic alterations in European BTC cohorts remain limited.
Jorine Arnouts +14 more
wiley +1 more source
Explaining Episodes of High Inflation: Demand‐ and Supply‐Side Drivers in Times of Uncertainty
International Journal of Finance &Economics, EarlyView.ABSTRACT In this paper, we investigate the extent to which uncertainty anticipates episodes of high inflation in 30 economies worldwide. Our analysis accounts for several factors, including inflation expectations, real global economic activity, and supply chain disruptions.
Maria‐Eleni K. Agoraki +2 more
wiley +1 more source
Pancreatic ductal adenocarcinoma (PDAC) is known to use glutamine to improve redox balance and proliferation rate. This study aimed to investigate the interference of the RAS-MEK pathway in PDAC cell lines, with their redox homeostasis and a potential ...
Wittel, Uwe A. +5 more
core +1 more source
Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation
iNew Medicine, EarlyView.The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li +11 more
wiley +1 more source