Results 191 to 200 of about 231,542 (282)

Distant intracranial failure in melanoma brain metastases treated with stereotactic radiosurgery in the era of immunotherapy and targeted agents [PDF]

, 2017
Abraham, Christopher, Acharya, Sahaja, Chicoine, Michael, Dowling, Joshua, Dunn, Gavin, Huang, Jiayi, Keller, Jesse, Leuthardt, Eric, Mahmood, Mustafaa, Mullen, Daniel, Perkins, Stephanie M, Rich, Keith, Robinson, Clifford G, Tsien, Christina I, Yang, Deshan   +14 more
core   +2 more sources

Clinical and Genetic Landscape of Glioblastoma, IDH‐Wildtype With FGFR Gene Family Alterations

Cancer Science, EarlyView.
We analyzed 1076 cases of glioblastoma, IDH‐wildtype (GBM, IDH‐wt) using the C‐CAT genomic database to clarify the clinical and genetic features of FGFR alterations. FGFR::TACC fusions and FGFR1 mutations were identified in distinct subsets and were associated with unique co‐mutation patterns.
Yasuhito Kegoya, Yoshihiro Otani, Ryo Mizuta, Ryosuke Ikemachi, Mako Kamiura, Joji Ishida, Shinichi Toyooka, Daisuke Ennishi, Shuta Tomida, Shota Tanaka   +9 more
wiley   +1 more source

Systemic Molecularly Targeted Therapies for Neoadjuvant and Salvage Craniopharyngioma: A Contemporary Narrative Review. [PDF]

Biomedicines
Neubecker JJ, Griepp DW, Turnbull JP, Caskey J, Desai S, Mansour A, Ahmed R, Beggs A, Griepp ATK, Heitkotter H, Claus CF, Richards BF, Kelkar PS.   +12 more
europepmc   +1 more source

MEK Inhibitor AZD8330 [PDF]

, 2020
openaire   +1 more source

Transcriptional Reinforcement of the HER2–RAS Network in HER2‐Positive Gastric Cancer: The RUNX–SOS1 Axis in Context

Cancer Science, EarlyView.
RUNX‐dependent transcriptional control of SOS1 reinforces HER2–RAS signaling and may attenuate responses to HER2‐targeted therapies in HER2‐positive gastric cancer. ABSTRACT HER2‐positive gastric cancer represents a distinct molecular subtype characterized by chromosomal instability, variable HER2 amplification, and substantial intratumoral ...
Tatsuya Masuda, Takayoshi Watanabe, Toshinori Ozaki, Yasuhiko Kamikubo   +3 more
wiley   +1 more source

MEK solvent power... [PDF]

Chemical & Engineering News Archive, 1960
openaire   +1 more source

Reliability and Construct Validity of a Questionnaire for Assessment of Patient‐Reported Outcomes in Implant Dentistry

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives The study aimed to evaluate the reliability and construct validity of a questionnaire assessing patient‐reported outcomes following dental implant rehabilitation. Material and Methods A questionnaire was mailed to patients 8 years posttreatment to assess experiences with dental implant therapy, including satisfaction, oral function,
Tonje Moen Eckhoff, Erik Klepsland Mauland, Anders Verket, Elisabeth Lind Melbye   +3 more
wiley   +1 more source

PD0325901 alleviates thrombin-inhibited osteogenic differentiation through an IL-1β-activated feedback loop between MEK-Erk1/2 and NF-κB signal pathways: insights from bioinformatics and experimental verification. [PDF]

Front Immunol
Ge YS, Huang CM, Shen J, Meng TT, Zhao MJ, Yin JL, Huang XH, Chen LL, Luo JH, Zhai YQ, Du JW, Wang YL, Wang XZ, Sun PP, Ding DF.   +14 more
europepmc   +1 more source

Spatiotemporal patterns of elephant and chimpanzee occurrence amid hunting in an unprotected African rainforest

Conservation Science and Practice, EarlyView.
We used long‐term data (2008–2023) from an unprotected African rainforest facing hunting pressure and impending logging to model how Nigeria‐Cameroon chimpanzees and African forest elephants respond to hunting. We found that elephant occurrence declined with increasing terrain ruggedness and was not affected by hunting.
Vianny Rodel Vouffo Nguimdo, Ekwoge Enang Abwe, Marcel Eyong Ketchen, Daniel Mbouombouo Mfossa, Abwe Enang Abwe, Nelson Ekole Betobe, Robin Whytock, Mathias W. Tobler, Johannes Kamp, Bethan J. Morgan, Matthias Waltert, Mahmood Soofi   +11 more
wiley   +1 more source

Dissecting the MAPK signaling landscape in malignant melanoma: from BRAF and NRAS mutations to precision combination therapies. [PDF]

Front Cell Dev Biol
Fang X, Wang S, Fu S.
europepmc   +1 more source