Results 51 to 60 of about 13,359 (150)

Out of the Ordinary, but Not Out of the Question: Atypia in Pancreatic Lesions Is Not Always Carcinoma

Cytopathology, EarlyView.
An incidental pancreatic lesion in a 69‐year‐old woman was sampled by EUS‐guided fine‐needle biopsy. Integrated cytopathological and histopathological evaluation with immunochemical staining supported organ‐preserving surgery. ABSTRACT Pancreatic perivascular epithelioid cell tumours (PEComas) are exceptionally rare mesenchymal neoplasms.
Maja Kebe Radulovic, Branislava Rankovic, Ajda Toni, Margareta Zlajpah, Darko Siuka   +4 more
wiley   +1 more source

Primary Pulmonary Perivascular Epithelioid Cell Tumour (PEComa): A Case Report

Respirology Case Reports
Perivascular epithelioid cell tumour (PEComa) is a rare mesenchymal neoplasm; lung is an exceptional primary site. Herein, we present a surgically resected case of primary pulmonary PEComa and discuss its clinicopathologic features in comparison with ...
Yu Sugimoto, Takeshi Hanagiri, Syuhei Ashikari, Takashi Iwanami, Jongkun Park   +4 more
doaj   +1 more source

Melanogenesis inhibition activity of floralginsenoside A from Panax ginseng berry

Journal of Ginseng Research, 2017
Background: Panax ginseng is a traditional herb used for medicinal purposes in eastern Asia. P. ginseng contains various ginsenosides with pharmacological effects.
Dae Young Lee, Jongsung Lee, Yong Tae Jeong, Geon Hee Byun, Jin Hee Kim   +4 more
doaj   +1 more source

Evaluating Vitamin C Mesotherapy for Gingival Depigmentation: An Analysis of TGF-β1 and E-cadherin Expression in Oral Epithelial Melanization. (Histological, histochemical and immunohistochemical study).

The Egyptian Journal of Histology
Background: Gingival melanin pigmentation is a widely acknowledged aesthetic concern. Current depigmentation methods often involve invasive approaches, driving a rising demand for exploring minimally invasive alternatives like vitamin C mesotherapy ...
Fatma Saad, Rania. A Fahmy
doaj   +1 more source

Clinicopathological and molecular comparison of eosinophilic solid and cystic renal cell carcinoma and TFEB‐amplified renal cell carcinoma: a comprehensive study of 15 cases

Histopathology, EarlyView.
This study supports the need for ancillary testing to diagnose ESC‐RCC versus TFEB‐amplified RCC, as neither morphology nor immunohistochemistry is sufficiently specific to distinguish these entities. The underlying molecular drivers in each tumour are pathogenic TSC1 or TSC2 gene variants in ESC‐RCC and TFEB gene amplification in TFEB‐amplified RCC ...
Hayley Zullow, Melissa Y. Tjota, Jung Woo Kwon, Tatjana Antic   +3 more
wiley   +1 more source

Inhibitory Effect of Corn Silk on Skin Pigmentation

Molecules, 2014
In this study, the inhibitory effect of corn silk on melanin production was evaluated. This study was performed to investigate the inhibitory effect of corn silk on melanin production in Melan-A cells by measuring melanin production and protein ...
Sang Yoon Choi, Yeonmi Lee, Sung Soo Kim, Hyun Min Ju, Ji Hwoon Baek, Chul-Soo Park, Dong-Hyuk Lee   +6 more
doaj   +1 more source

Novel and emerging cutaneous soft tissue tumours

Histopathology, EarlyView.
This review outlines the defining histopathological, immunophenotypic and molecular features of novel and emerging cutaneous soft tissue tumours, including hybrid superficial ALK‐rearranged myxoid spindle cell neoplasm/epithelioid fibrous histiocytoma, superficial neurocristic tumour, ALK‐rearranged epithelioid vascular neoplasm and MITF pathway ...
Saba Shafi, Josephine K Dermawan
wiley   +1 more source

Antigen-specificity and DTIC before peptide-vaccination differently shape immune-checkpoint expression pattern, anti-tumor functionality and TCR repertoire in melanoma patients

OncoImmunology, 2018
We have recently described that DNA-damage inducing drug DTIC, administered before peptide (Melan-A and gp100)-vaccination, improves anti-tumor CD8+ Melan-A-specific T-cell functionality, enlarges the Melan-A+ TCR repertoire and impacts the overall ...
Belinda Palermo, Ornella Franzese, Cosmo Di Donna, Mariangela Panetta, Concetta Quintarelli, Isabella Sperduti, Novella Gualtieri, Maria Laura Foddai, Enrico Proietti, Virginia Ferraresi, Gennaro Ciliberto, Paola Nisticò   +11 more
doaj   +1 more source

Enhancement of the leptomeninges in a young man

Brain Pathology, EarlyView.
Jayden Ray, Mohammad Alberawi, Andrew Bauer, Kar‐Ming Fung, Erika Santos Horta, Lorraina J. Robinson   +5 more
wiley   +1 more source

The Biological Basis of the Merlin CP‐GEP Assay: Integrin Signaling and Early Metastatic Competence in Cutaneous Melanoma

International Journal of Dermatology, EarlyView.
Merlin CP‐GEP integrates mechanistic insights into a clinically actionable assay to predict SLN metastasis risk and inform personalized management of cutaneous melanoma. ABSTRACT The recent inclusion of the Merlin clinicopathologic–gene expression profile (CP‐GEP) assay in the National Comprehensive Cancer Network (NCCN) Melanoma Guidelines represents ...
Frank Z. Jing, Alexander Meves
wiley   +1 more source