Results 171 to 180 of about 58,907 (217)

Obesogenic effects of warm temperature involve feeding adaptation by preoptic area leptin receptor neurons. [PDF]

Commun Biol
Kaiser L, Lee N, Zaunbrecher K, Kinney C, Williams J, Smith M, Noland RC, Yu S, Morrison CD, Berthoud HR, Münzberg H.   +10 more
europepmc   +1 more source

Polymorphism of Melanocortin Receptor Genes-Association with Inflammatory Traits and Diseases. [PDF]

Diseases
Bardhan M, Anand A, Javed A, Chilo MA, Khan N, Garg T, Surana A, Huang H, Samim MM, Suresh V, Khare A, Menon B, Kundu T.   +12 more
europepmc   +1 more source

Modulating food intake by nasal application of peptides targeting melanocortin 4 receptor and ghrelin receptor systems. [PDF]

Brain Commun
Özbay B, Jülke EM, List M, Nowicki M, Els-Heindl S, Immig K, Mörl K, Bechmann I, Beck-Sickinger AG.   +8 more
europepmc   +1 more source

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Pharmacological characterization of three chicken melanocortin-3 receptor mutants

Domestic Animal Endocrinology, 2021
The melanocortin-3 receptor (MC3R) is a G protein-coupled receptor and potentially important in production traits. Three naturally occurring mutations (M54L, G104S, and L151R) in chicken MC3R (cMC3R) were reported previously to be associated with production traits.
H.-J. Zhang, Z.-H. Cui, M. Liu, T.-Q. Min, X. Xiao, Z.-Q. Wang, Y.-X. Tao   +6 more
openaire   +2 more sources

Melanocortin 3 receptors control crystal‐induced inflammation

The FASEB Journal, 2006
In this study we have characterized the anti‐inflammatory profile of a selective melanocortin type 3 receptor (MC3‐R) ligand [D‐Trp 8 ]‐γ‐MSH, validating in vitro results with analyses in mice deficient for this receptor subtype.
Stephen J, Getting, Connie W, Lam, Airu S, Chen, Paolo, Grieco, Mauro, Perretti   +4 more
openaire   +2 more sources

The polymorphisms of bovine melanocortin-3 receptor pseudogene

Research in Veterinary Science, 2011
Mammalian melanocortin-3 receptor (MC3R) plays an important role in the central control of energy homeostasis, and several functional polymorphisms of mc3r have been detected. Interestingly, the bovine mc3r was a pseudogene, and its polymorphisms and function remain to be investigated.
C L, Zhang, Y H, Wang, C Z, Lei, X T, Fang, H, Chen   +4 more
openaire   +2 more sources

Molecular Characterization of Human Melanocortin-3 Receptor Ligand−Receptor Interaction

Biochemistry, 2006
Melanocortin-3 receptor (MC3R), primarily expressed in the hypothalamus, plays an important role in the regulation of energy homeostasis. MC3R-deficient (MC3R(-)(/)(-)) mice demonstrate increased fat mass, higher feeding efficiency, hyperleptinaemia, and mild hyperinsulinism.
Min, Chen, Charles J, Aprahamian, Ahmet, Celik, Keith E, Georgeson, W Timothy, Garvey, Carroll M, Harmon, Yingkui, Yang   +6 more
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Rattus norvegicus melanocortin 3 receptor: A corrected sequence

Peptides, 2005
Examination of the Rattus norvegicus genome reveals differences in the melanocortin 3 receptor (MC3R) compared with the published sequence (accession X70667). To clarify these differences, we used RT-PCR to clone MC3R from Sprague Dawley rats. These efforts revealed a sequence for the rat MC3R consistent with that predicted by the rat genome, but ...
Derek, Daniels, Aae, Suzuki, Edan, Shapiro, Laiyi, Luo, Daniel K, Yee, Steven J, Fluharty   +5 more
openaire   +2 more sources