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Design, synthesis and characterisation of gurmarin and melanocortin analogues of gurmarin [PDF]
Eliasen, Rasmus
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Melanocortin 4 receptor mutations become common
Cell Metabolism, 2021In a new paper, Wade et al. (2021) analyzed the frequency of MC4R loss-of-function (LoF) mutations in a population-based Avon Longitudinal Study of Parents and Children. The frequency was 1 in 337 and the authors showed that MC4R LoF variants significantly correlated with increased body weight and fat mass in children and adults (cumulating in ...
Peter, Kühnen +2 more
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