Results 141 to 150 of about 60,692 (262)

Editorial: Melanocortins and melanocortin receptors in the regulation of inflammation: mechanisms and novel therapeutic strategies

Frontiers in Immunology, 2023
Petteri Rinne, Petteri Rinne, Andrew W. Taylor, Trinidad Montero-Melendez   +3 more
doaj   +1 more source

Widespread dynamic and pleiotropic expression of the melanocortin-1-receptor (MC1R) system is conserved across chick, mouse and human embryonic development [PDF]

, 2017
Anna Thomas, Pauline Heux, Chloe Santos, Wisenave Arulvasan, Nita Solanky, Magalie E. Carey, Dianne Gerrelli, Veronica A. Kinsler, Heather Etchevers   +8 more
openalex   +1 more source

Melanocortin 1 receptor ligands and methods of use

, 2016
The subject invention pertains to a modified MC1R peptide ligand comprising a peptide that is a melanocortin 1 receptor (MC1R) ligand and a functionality or linker, such as a click functionality, for conjugation to a surface or agent. The modified MC1R peptide ligand can be coupled, e.g., via a click reaction with a complementary click functionality ...
David L. Morse, Victor J. Hruby, Jonathan L. Sessler, Robert J. Gillies, Josef Vagner, Kevin N. Sill, Natalie M. Barkey, Narges K. Tafreshi, Christian Preihs   +8 more
openaire   +2 more sources

A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA. [PDF]

Int J Mol Sci, 2023
Cerdido S, Sánchez-Beltrán J, Lambertos A, Abrisqueta M, Padilla L, Herraiz C, Olivares C, Jiménez-Cervantes C, García-Borrón JC.   +8 more
europepmc   +1 more source

UV AND MELANOCORTIN 1 RECEPTORS

, 2010
Les ultraviolets A (UVA) sont carcinogènes et produisent des espèces réactives de l'oxygène (ERO). Le récepteur à la mélanocortine de type 1 (MC1R) est un récepteur couplé aux protéines G (RCPG) qui est impliqué dans la mélanogénèse et dans l'inflammation cutanée.
openaire   +1 more source

Absorption, metabolism, and excretion of [¹⁴ C]dersimelagon, an investigational oral selective melanocortin 1 receptor agonist, in preclinical species and healthy volunteers. [PDF]

Pharmacol Res Perspect, 2023
Tsuda M, Ogawa K, Endou T, Goto T, Ogasawara Y, Ogasawara A.   +5 more
europepmc   +1 more source

Curcumin ameliorates oxaliplatin-induced allodynia response and melanocortin downregulation in the spinal cord

Research Results in Pharmacology
Introduction: Oxaliplatin is a platinum-based chemotherapy agent that often causes chemotherapy-induced peripheral neuropathy (CIPN). This effect limits the potential activity and decreases the cancer patient’s quality of life. Melanocortin and transient
Alma Nuril Aliya, Luke Wongso, Diah Ayu Wakita Trimanda , Risda Maulida, I Nengah Budi Sumartha, Samirah Samirah, Abdulloh Machin, Long Chiau Ming, Abdelhakim Bouyahya, Mahardian Rahmadi, Junaidi Khotib, Сhrismawan Ardianto   +11 more
doaj   +1 more source

Variation of the melanocortin 1 receptor gene in the macaques [PDF]

, 2008
Kazuhiro Nakayama, Takayoshi Shotake, Osamu Takeneka, Takafumi Ishida   +3 more
openalex   +1 more source

Hematopoietic-specific melanocortin 1 receptor signaling protects against nephrotoxic serum nephritis and mediates the beneficial effect of melanocortin therapy. [PDF]

Kidney Int, 2023
Guan X, Chen B, Malhotra DK, Gohara AF, Dworkin LD, Gong R.   +5 more
europepmc   +1 more source

Podocyte Melanocortin 1 Receptor Mediated Signaling

, 2015
Treatment of patients with nephrotic syndrome (NS) is currently unspecific and directed at ameliorating the symptoms rather than eliminating the cause. NS is actually a multitude of glomerular diseases characterized by poorly understood disease mechanisms and symptoms that include proteinuria, hypoalbuminemia and edema.
openaire