Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight. [PDF]
Neuropeptide Y (NPY) is widely expressed in the central nervous system and influences many physiological processes. It is located within the rat quantitative trait locus (QTL) for alcohol preference on chromosome 4.
Bell, Richard L. +8 more
core +1 more source
ABSTRACT Aim Mediterranean peninsulas typically harbour high intraspecific genetic diversity associated with long‐term persistence in multiple glacial refugia. However, some widespread taxa show unexpectedly shallow phylogeographic structure. Here, we investigate which historical processes can generate a pattern of strong genetic depletion within a ...
Daniele Salvi +5 more
wiley +1 more source
Pharmacogenomic and structural analysis of constitutive G-protein coupled receptor activity [PDF]
Premi a l'excel·lència investigadora. Àmbit de les Ciències de la Salut. 2008G-protein coupled receptors (GPCRs) respond to a chemically diverse plethora of signal transduction molecules.
Aldo Jongejan +29 more
core +3 more sources
Noradrenergic inhibition of definitive POMC neurons through direct and indirect mechanisms
Norepinephrine and the α2‐adrenoceptor agonist UK 14,304 robustly inhibit definitive arcuate POMC neurons. Direct inhibition is mediated by ADRA2A‐dependent activation of potassium conductances, while additional indirect mechanisms also contribute. In vivo, inducible POMC‐specific Adra2a deletion minimally affects energy balance and modestly impairs ...
Olivier Lavoie +6 more
wiley +1 more source
Neuropeptide Y and melanocortin receptors in fish: regulators of energy homeostasis. [PDF]
Hou ZS, Wen HS.
europepmc +1 more source
Amplification of the Melanocortin-1 Receptor in Nephrotic Syndrome Identifies a Target for Podocyte Cytoskeleton Stabilization [PDF]
Lovisa Bergwall +10 more
openalex +1 more source
Abstract Glaucoma is a chronic optic neuropathy characterized by progressive vision loss. A previous study from our group showed that glaucoma‐induced retinal degeneration disrupts photic signaling to the suprachiasmatic nucleus (SCN), altering the molecular components of the central circadian clock.
Pietra Souza Barsanele +7 more
wiley +1 more source
Aged Brains Express Less Melanocortin Receptors, Which Correlates with Age-Related Decline of Cognitive Functions. [PDF]
Zhou Y +7 more
europepmc +1 more source
Morphometric Traits and Melanocortin 1 Receptor (MC1R) Gene Polymorphism of Indonesian Muscovy Ducks of Different Plumage Color Population [PDF]
Ismoyowati Ismoyowati +4 more
openalex +1 more source
ABSTRACT Background Hyperpigmentation, caused by excessive melanin accumulation, is a significant cosmetic concern in dermatology. Natural compounds are receiving attention as safe and effective skin‐lightening agents due to their antioxidant properties and ability to inhibit melanin synthesis.
Jung‐Wook Kang +4 more
wiley +1 more source

