Andrology, Volume 14, Issue 4, Page 978-991, May 2026.Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre +5 more
wiley +1 more source
Effect of NDP-a-MSH on PPAR-c and –b Expression and Anti-Inflammatory Cytokine Release in Rat Astrocytes and Microglia [PDF]
, 2013 Brain inflammation plays a central role in numerous brain pathologies. Microglia and astrocytes are the main effector cells that become activated when an inflammatory process takes place within the central nervous system. a-melanocytestimulating hormone (
Carniglia, Lila +3 more
core +1 more source
Global consensus on the management of melanin hyperpigmentation disorders
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 760-772, May 2026.A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron +9 more
wiley +1 more source
Divergent effects of central melanocortin signalling on fat and sucrose preference in humans
Nature Communications, 2016 Hypothalamic melanocortin-4-receptors (MC4R) regulate food preference in rodents, but their role in humans is unclear. Here, the authors perform food preference and liking tests in humans with MC4R mutations and find that they prefer fatty food more, but
Agatha A. van der Klaauw +9 more
doaj +1 more source
The blue lizard spandrel and the island syndrome
BMC Evolutionary Biology, 2010 Background Many small vertebrates on islands grow larger, mature later, lay smaller clutches/litters, and are less sexually dimorphic and aggressive than their mainland relatives. This set of observations is referred to as the 'Island Syndrome'.
Monti Daria M +8 more
doaj +1 more source
Adrenalectomy alters the sensitivity of the central nervous system melanocortin system [PDF]
, 2003 Removal of adrenal steroids by adrenalectomy (ADX) reduces food intake and body weight in rodents and prevents excessive weight gain in many genetic and dietary models of obesity. Thus, glucocorticoids appear to play a key role to promote positive energy
Clegg, DJ +11 more
core +2 more sources
Defining Acquired Hypothalamic Obesity: An Expert Call for Unified Diagnosis and Therapeutic Action
Diabetes, Obesity and Metabolism, EarlyView.
Hanneke M. van Santen +7 more
wiley +1 more source
Melanocortin-1 receptor ( MC1R ) genotypes do not correlate with size in two cohorts of medium-to-giant congenital melanocytic nevi [PDF]
, 2020 Neus Calbet‐Llopart +13 more
openalex +1 more source
Melanocortin 1 receptor (MC1R) expression as a marker of progression in melanoma [PDF]
, 2023 David Su +6 more
openalex +1 more source
Habitat Fragmentation in Urbanized Landscapes Favors Bird Species With Darker Plumage
Ecology and Evolution, Volume 16, Issue 4, April 2026.Using long‐term breeding bird survey data from 30 remnant woodlot patches within a rapidly urbanizing landscape in southwest China, we demonstrate that species with darker plumage are more likely to persist in highly fragmented habitats. The pattern is slightly more pronounced in males than in females.
Yan Wang +7 more
wiley +1 more source