Results 221 to 230 of about 44,230 (269)

Central effects of bile acids on feed intake and mRNA expression of appetite-related neuropeptides in layer-type chicks. [PDF]

Poult Sci
Ghashghaei E, Mijiyawa A, Wang M, Zendehdel M, Lin H.   +4 more
europepmc   +1 more source

Obesogenic effects of warm temperature involve feeding adaptation by preoptic area leptin receptor neurons. [PDF]

Commun Biol
Kaiser L, Lee N, Zaunbrecher K, Kinney C, Williams J, Smith M, Noland RC, Yu S, Morrison CD, Berthoud HR, Münzberg H.   +10 more
europepmc   +1 more source

Functional characterisation of obesity-associated MRAP2 variants on MC4R and GHSR signalling. [PDF]

Hum Mol Genet
Rodríguez Rondón AV, Prins K, Volker F, van der Walle EEPL, de Groot CJ, van der Akker ELT, van Rossum EFC, van Haelst MM, Delhanty PJD, Visser JA.   +9 more
europepmc   +1 more source

Modulating food intake by nasal application of peptides targeting melanocortin 4 receptor and ghrelin receptor systems. [PDF]

Brain Commun
Özbay B, Jülke EM, List M, Nowicki M, Els-Heindl S, Immig K, Mörl K, Bechmann I, Beck-Sickinger AG.   +8 more
europepmc   +1 more source

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Melanocortin receptors: perspectives for novel drugs

European Journal of Pharmacology, 1999
The cloning of five different subtypes of melanocortin receptor subtypes have recently opened up new possibilities for the development of drugs. The physiological roles of the five melanocortin receptors have started to become understood, and compounds with selective actions on some of the five subtypes have become available. Presently, most clinically
openaire   +4 more sources

Characterization of Melanocortin Receptors

Current Protocols in Pharmacology, 2003
AbstractThis unit describes a Scintillation Proximity Assay (SPA) for the measurement of ligand binding to melanocortin receptors (MCRs) using membranes prepared from cell lines stably expressing recombinant MCRs. It provides a facile method for determining the affinity of compounds at MC1R, MC3R, MC4R, or MC5R.
Aaron S, Goetz, Diane M, Ignar
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New ligands for melanocortin receptors

International Journal of Obesity, 2008
Named originally for their effects on peripheral end organs, the melanocortin system controls a diverse set of physiological processes through a series of five G-protein-coupled receptors and several sets of small peptide ligands. The central melanocortin system plays an essential role in homeostatic regulation of body weight, in which two alternative ...
C B, Kaelin, S I, Candille, B, Yu, P, Jackson, D A, Thompson, M A, Nix, J, Binkley, G L, Millhauser, G S, Barsh   +8 more
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Melanocortin Receptors and Erectile Function

European Urology, 2004
Review the historical and current evidence that suggests that activation of melanocortin receptors modulates erectile activity.The available literature was reviewed.Melanocortin peptides derived from the pro-opiomelanocortin (POMC) precursor protein exert a host of diverse physiological effects in the periphery and in the CNS through interactions with ...
William J, Martin, D Euan, MacIntyre
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Melanocortin-5 receptor and sebogenesis

European Journal of Pharmacology, 2011
The melanocortins (α-MSH, β-MSH, γ-MSH, and ACTH) bind to the melanocortin receptors and signal through increases in cyclic adenosine monophosphate to induce biological effects. The melanocortin MC(5) and MC(1) receptors are expressed in human sebaceous glands, which produce sebum, a lipid mixture of squalene, wax esters, triglycerides, cholesterol ...
Li, Zhang, Wen-Hwa, Li, Michael, Anthonavage, Apostolos, Pappas, Dianne, Rossetti, Druie, Cavender, Miri, Seiberg, Magdalena, Eisinger   +7 more
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