Results 81 to 90 of about 34,268 (231)

The blue lizard spandrel and the island syndrome

open access: yesBMC Evolutionary Biology, 2010
Background Many small vertebrates on islands grow larger, mature later, lay smaller clutches/litters, and are less sexually dimorphic and aggressive than their mainland relatives. This set of observations is referred to as the 'Island Syndrome'.
Monti Daria M   +8 more
doaj   +1 more source

Developmental Plasticity and Behavioural Evolution in Rodents: Insights From African Striped Mice (Rhabdomys)

open access: yesJournal of Zoology, EarlyView.
Our review synthesizes how early‐life experiences shape behavioural development in rodents, drawing on developmental plasticity, non‐genetic inheritance and epigenetic mechanisms. Using African striped mice (Rhabdomys) and other small mammal systems as case studies, it presents an integrative framework linking parental care, developmental pathways and ...
N. Pillay, T. L. Rymer
wiley   +1 more source

Melanocortin 1 receptor (MC1R) expression as a marker of progression in melanoma [PDF]

open access: green, 2023
David Su   +6 more
openalex   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

open access: yesObesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid   +22 more
wiley   +1 more source

Cannabinoid, melanocortin and opioid receptor expression on DRD1 and DRD2 subpopulations in rat striatum

open access: yesFrontiers in Neuroanatomy, 2014
The striatum harbors two neuronal populations that enable action selection. One population represents the striatonigral pathway, expresses the dopamine receptor D1 (DRD1) and promotes the execution of motor programs, while the other population represents
Ralph J Oude-Ophuis   +4 more
doaj   +1 more source

Setmelanotide in Bardet‐Biedl Syndrome: A Case Report

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith   +2 more
wiley   +1 more source

Striking Suture Zone Mismatch Between Nuclear and Mitochondrial Markers in North African Chalcides ocellatus (Squamata: Scincidae)

open access: yesZoologica Scripta, EarlyView.
ABSTRACT Linnaean and Wallacean shortfalls remain pervasive even among common and widespread Mediterranean taxa, limiting our understanding of evolutionary history and species boundaries. The Ocellated Skink Chalcides ocellatus complex illustrates this issue, with disputed subspecific taxonomy and deep mitochondrial divergences across North Africa and ...
Paul Doniol‐Valcroze   +7 more
wiley   +1 more source

ACTH antagonists

open access: yesFrontiers in Endocrinology, 2016
ACTH acts via a highly selective receptor that is a member of the melanocortin receptor subfamily of type 1 G protein-coupled receptors. The ACTH receptor, also known as the melanocortin 2 receptor (MC2R) is unusual in that it is absolutely dependent on ...
Adrian John Clark   +6 more
doaj   +1 more source

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