Results 41 to 50 of about 92,933 (386)

High correlation between skin color based on CIELAB color space, epidermal melanocyte ratio, and melanocyte melanin content [PDF]

open access: yesPeerJ, 2018
Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor ...
Wen-Shyan Huang   +9 more
doaj   +2 more sources

Melanocyte progenitor cells reside in human subcutaneous adipose tissue.

open access: yesPLoS ONE, 2021
Based on the assumption that some progenitor cells in an organ might reside in neighboring adipose tissue, we investigated whether melanocyte progenitor cells reside in human subcutaneous adipose tissue.
Yuri Ikeda   +5 more
doaj   +1 more source

Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling

open access: yeseLife, 2019
Preventing terminal differentiation is important in the development and progression of many cancers including melanoma. Recent identification of the BMP ligand GDF6 as a novel melanoma oncogene showed GDF6-activated BMP signaling suppresses ...
Alec K Gramann   +3 more
doaj   +1 more source

YY1 regulates melanocyte development and function by cooperating with MITF. [PDF]

open access: yesPLoS Genetics, 2012
Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency and
Juying Li   +10 more
doaj   +1 more source

Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials

open access: yesExperimental Dermatology, 2019
Skin evolves essential appendages and indispensable types of cells that synergistically insulate the body from environmental insults. Residing in the specific regions in the skin such as epidermis, dermis and hair follicle, melanocytes perform an array ...
W. Qiu, C. Chuong, Mingxing Lei
semanticscholar   +1 more source

Melanocortin 1 receptor targeted imaging of melanoma with gold nanocages and positron emission tomography [PDF]

open access: yes, 2018
Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirable ...
Black, Kvar   +8 more
core   +2 more sources

Race Does Not Predict Melanocyte Heterogeneous Responses to Dermal Fibroblast-Derived Mediators. [PDF]

open access: yesPLoS ONE, 2015
Abnormal pigmentation following cutaneous injury causes significant patient distress and represents a barrier to recovery. Wound depth and patient characteristics influence scar pigmentation.
Pornthep Sirimahachaiyakul   +8 more
doaj   +1 more source

Type II Opsins in the Eye, the Pineal Complex and the Skin of Xenopus laevis: Using Changes in Skin Pigmentation as a Readout of Visual and Circadian Activity

open access: yesFrontiers in Neuroanatomy, 2022
The eye, the pineal complex and the skin are important photosensitive organs. The African clawed frog, Xenopus laevis, senses light from the environment and adjusts skin color accordingly.
Gabriel E. Bertolesi   +4 more
doaj   +1 more source

The melanocyte lineage in development and disease

open access: yesDevelopment, 2015
Melanocyte development provides an excellent model for studying more complex developmental processes. Melanocytes have an apparently simple aetiology, differentiating from the neural crest and migrating through the developing embryo to specific locations
R. Mort, I. Jackson, E. Patton
semanticscholar   +1 more source

Bridging scales in cancer progression: Mapping genotype to phenotype using neural networks [PDF]

open access: yes, 2014
In this review we summarize our recent efforts in trying to understand the role of heterogeneity in cancer progression by using neural networks to characterise different aspects of the mapping from a cancer cells genotype and environment to its phenotype.
Anderson, Alexander R. A.   +2 more
core   +1 more source

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