Results 41 to 50 of about 92,933 (386)
High correlation between skin color based on CIELAB color space, epidermal melanocyte ratio, and melanocyte melanin content [PDF]
Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor ...
Wen-Shyan Huang+9 more
doaj +2 more sources
Melanocyte progenitor cells reside in human subcutaneous adipose tissue.
Based on the assumption that some progenitor cells in an organ might reside in neighboring adipose tissue, we investigated whether melanocyte progenitor cells reside in human subcutaneous adipose tissue.
Yuri Ikeda+5 more
doaj +1 more source
Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling
Preventing terminal differentiation is important in the development and progression of many cancers including melanoma. Recent identification of the BMP ligand GDF6 as a novel melanoma oncogene showed GDF6-activated BMP signaling suppresses ...
Alec K Gramann+3 more
doaj +1 more source
YY1 regulates melanocyte development and function by cooperating with MITF. [PDF]
Studies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency and
Juying Li+10 more
doaj +1 more source
Skin evolves essential appendages and indispensable types of cells that synergistically insulate the body from environmental insults. Residing in the specific regions in the skin such as epidermis, dermis and hair follicle, melanocytes perform an array ...
W. Qiu, C. Chuong, Mingxing Lei
semanticscholar +1 more source
Melanocortin 1 receptor targeted imaging of melanoma with gold nanocages and positron emission tomography [PDF]
Purpose: Melanoma is a lethal skin cancer with unmet clinical needs for targeted imaging and therapy. Nanoscale materials conjugated with targeting components have shown great potential to improve tumor delivery efficiency while minimizing undesirable ...
Black, Kvar+8 more
core +2 more sources
Race Does Not Predict Melanocyte Heterogeneous Responses to Dermal Fibroblast-Derived Mediators. [PDF]
Abnormal pigmentation following cutaneous injury causes significant patient distress and represents a barrier to recovery. Wound depth and patient characteristics influence scar pigmentation.
Pornthep Sirimahachaiyakul+8 more
doaj +1 more source
The eye, the pineal complex and the skin are important photosensitive organs. The African clawed frog, Xenopus laevis, senses light from the environment and adjusts skin color accordingly.
Gabriel E. Bertolesi+4 more
doaj +1 more source
The melanocyte lineage in development and disease
Melanocyte development provides an excellent model for studying more complex developmental processes. Melanocytes have an apparently simple aetiology, differentiating from the neural crest and migrating through the developing embryo to specific locations
R. Mort, I. Jackson, E. Patton
semanticscholar +1 more source
Bridging scales in cancer progression: Mapping genotype to phenotype using neural networks [PDF]
In this review we summarize our recent efforts in trying to understand the role of heterogeneity in cancer progression by using neural networks to characterise different aspects of the mapping from a cancer cells genotype and environment to its phenotype.
Anderson, Alexander R. A.+2 more
core +1 more source