Feeding Stimulates Sphingosine-1-Phosphate Mobilization in Mouse Hypothalamus. [PDF]
, 2019 Previous studies have shown that the sphingolipid-derived mediator sphingosine-1-phosphate (S1P) reduces food intake by activating G protein-coupled S1P receptor-1 (S1PR1) in the hypothalamus.
Misto, Alessandra +3 more
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Journal of Investigative Dermatology, 1979 Choroidal melanocytes of the eyes of postnatal animals are classified as postmitotic terminally differentiated cells. They have specific granules, the melanosomes, which undergo changes qualitatively and quantitatively correlated to the animal's increasing age.
openaire +3 more sources
Super-High Magnification Dermoscopy in 190 Clinically Atypical Pigmented Lesions
Diagnostics, 2023 Super-high (×400) magnification dermoscopy (D400) is a new non-invasive imaging technique that has been shown to add information for the differential diagnosis of melanocytic lesions in a pilot study.
Elisa Cinotti +8 more
doaj +1 more source
The role of extracellular vesicles in cutaneous remodeling and hair follicle dynamics [PDF]
, 2019 Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are cell-derived membranous structures that were originally catalogued as a way of releasing cellular waste products.
Carrasco, Elisa +2 more
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A Comparison Between Phorbol 12 Myristate 13 Acetate and Phorbol 12, 13 Dibutyrate in Human Melanocyte Culture [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Melanocyte culture is an integral part of the studies of skin biology and cosmetic applications. After the introduction of selective medium for the culture of human melanocyte using Phorbol 12-myristate13-acetate (PMA) in 1982, a lot of ...
Divya Padma, Kumar M.R. Bhat
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Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro
Cells, 2022 Detection and quantification of senescent cells remain difficult due to variable phenotypes and the absence of highly specific and reliable biomarkers. It is therefore widely accepted to use a combination of multiple markers and cellular characteristics ...
Tom Zimmermann +5 more
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Melanocytes and Skin Immunity [PDF]
Journal of Investigative Dermatology Symposium Proceedings, 2015 Melanocytes in skin are melanin-producing cells that are derived from the neural crest. They migrate during embryological development and localize in the epidermis and hair follicles where they pigment skin and hair (Nishimura, 2011). Melanocytes and their production of melanin pigment (a process termed melanogenesis) have important roles in cutaneous ...
Xing-Hua Gao +3 more
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Large Melanosome Complex Is Increased in Keratinocytes of Solar Lentigo
Cosmetics, 2017 Solar lentigo (SL) is characterized by macular lesions exhibiting epidermal hyperplasia combined with hyperpigmentation along with irregular elongation of epidermal rete ridges.
Kazuhisa Maeda
doaj +1 more source
Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]
, 2013 It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin +6 more
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MicroRNAs in melanoma development and resistance to target therapy [PDF]
, 2017 microRNAs constitute a complex class of pleiotropic post-transcriptional regulators of gene expression involved in the control of several physiologic and pathologic processes.
Ascierto, Paolo Antonio +7 more
core +1 more source