Results 101 to 110 of about 123,035 (391)

Origins of the avian neural crest: the role of neural plate-epidermal interactions [PDF]

, 1995
We have investigated the lineage and tissue interactions that result in avian neural crest cell formation from the ectoderm. Presumptive neural plate was grafted adjacent to non-neural ectoderm in whole embryo culture to examine the role of tissue ...
Bronner-Fraser, Marianne, Selleck, Mark A. J.   +1 more
core  

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Comparison of SOX-10, HMB-45, and Melan-A in Benign Melanocytic Lesions

Clinical, Cosmetic and Investigational Dermatology, 2021
Sabrina E Dass,1 Taryn Huizenga,2 Mehdi Farshchian,2 Darius R Mehregan2 1Wayne State University School of Medicine, Detroit, MI, USA; 2Department of Dermatology, Wayne State University, Detroit, MI, USACorrespondence: Mehdi FarshchianDepartment of ...
Dass SE, Huizenga T, Farshchian M, Mehregan DR   +3 more
doaj  

Neurocristic cutaneous hamartoma: Case report of a rare entity

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2019
Neurocristic cutaneous hamartoma (NCH) is a rare entity characterized by hamartomatous proliferation of melanocytic, neuroid, and mesenchymal tissues. It results from the aberrant development of the neural crest cells. A 29-year-old female presented with
B N Kumarguru, N Haripriya, A S Ramaswamy, M J Nirmala   +3 more
doaj   +1 more source

Mechanism underlying synergic activation of Tyrosinase promoter by MITF and IRF4 [PDF]

, 2017
Background: The transcription factor interferon regulatory factor 4 (IRF4) was identified to be involved in human pigmentation by genome-wide association studies (GWASs).
Cai, Xinzhang, Chen, Hongsheng, Feng, Yong, He, Chufeng, Li, Jiada, Liu, Huadie, Liu, Xueming, Liu, Yalan, Mei, Lingyun, Peng, Zhen, Song, Jian, Vleminckx, Kris   +11 more
core   +1 more source

Interferon-γ Induces Senescence in Normal Human Melanocytes

PLoS ONE, 2014
Background Interferon-γ (IFN-γ) plays an important role in the proceedings of vitiligo through recruiting lymphocytes to the lesional skin. However, the potential effects of IFN-γ on skin melanocytes and the subsequent contribution to the vitiligo ...
Suiquan Wang, Miao-ni Zhou, F. Lin, Dongyin Liu, W. Hong, L. Lu, Yiping Zhu, A. Xu   +7 more
semanticscholar   +1 more source

Recent advances in animal models for pathological scar research: A comprehensive review of experimental approaches and translational relevance

Animal Models and Experimental Medicine, EarlyView.
Animal models remain indispensable in the study of pathological scars, each offering unique advantages and constraints. Their integration with in vitro and ex vivo systems is key to developing personalized, clinically translatable antifibrotic therapies. Abstract Pathological scarring, manifested in the form of hypertrophic scars (HTS) and keloid scars
Diana‐Larisa Ancuța, Mariana Văduva, Cristin Coman, Iuliana Caraș   +3 more
wiley   +1 more source

Insights into human melanocyte development and characteristics through pluripotent stem cells combined with single-cell sequencing

iScience
Summary: Human pigment-related diseases are closely linked to melanocytes, yet our understanding of their development has largely relied on animal models.
Jie Yang, Zihan Wang, Hang Zhou, Yuyun Xiong, Yumei Li, Yun-wen Zheng, Liping Liu   +6 more
doaj   +1 more source

Aetiology and treatment of epidermal depigmentory disorder in humans [PDF]

, 2012
The epidermal depigmentary trigger in humans at post-natal level may occur with the toxification of skin organ with the endogenously produced melanocytotoxic hydrogen peroxide and subsequent formation of hydrogen peroxide- melanolipoprotein conjugate ...
S. S. Sawhney
core   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source