Results 121 to 130 of about 116,555 (410)

Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma [PDF]

open access: yes, 2009
Current treatment options for neuroblastoma fail to eradicate the disease in the majority of high-risk patients, clearly mandating development of innovative therapeutic strategies. Gene therapy represents a promising approach for reversing the neoplastic
Ardelt   +37 more
core   +2 more sources

Optimized reconstruction of the absorption spectra of kidney tissues from the spectra of tissue components using the least squares method

open access: yesJournal of Biophotonics, EarlyView.
The absorption coefficient spectra of healthy and cancerous kidney tissues were reconstructed from the absorption spectra of tissue components using constant weights. Both reconstructions allowed to calculate the concentrations of the tissue components and a comparison between the healthy and chromophobe renal cell carcinoma kidney showed an increase ...
Maria R. Pinheiro   +7 more
wiley   +1 more source

Gene Expression Analysis of Zebrafish Melanocytes, Iridophores, and Retinal Pigmented Epithelium Reveals Indicators of Biological Function and Developmental Origin

open access: yesPLoS ONE, 2013
In order to facilitate understanding of pigment cell biology, we developed a method to concomitantly purify melanocytes, iridophores, and retinal pigmented epithelium from zebrafish, and analyzed their transcriptomes. Comparing expression data from these
Charles W. Higdon   +2 more
semanticscholar   +1 more source

A feasibility study for a persistent homology based k-Nearest Neighbor search algorithm in melanoma detection [PDF]

open access: yesarXiv, 2016
Persistent Homology is a fairly new branch of Computational Topology which combines geometry and topology for an effective shape description of use in Pattern Recognition. In particular it registers through "Betti Numbers" the presence of holes and their persistence while a parameter ("filtering function") is varied.
arxiv  

Evans Medicine [PDF]

open access: yes, 1988
Newsletter of the Evans Memorial Department of Clinical Research and Preventive Medicine at University ...
University Hospital, Evans Memorial Department of Clinical Research and Preventive Medicine
core  

A modelling approach towards Epidermal homoeostasis control

open access: yes, 2007
In order to grasp the features arising from cellular discreteness and individuality, in large parts of cell tissue modelling agent-based models are favoured.
Barthel   +64 more
core   +1 more source

Diffuse Melanosis Cutis Under Immuno‐ and Targeted Therapy

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT In patients with highly advanced melanoma, rarely a diffuse melanosis cutis (DMC) can be noticed. Even though the condition is generally harmless itself, it can have a significant impact on the patient's well‐being as an obvious mark of the disease. DMC causes a grey or brown discoloration of the skin and mucous membranes. We report on a young
Christiane Cussigh   +3 more
wiley   +1 more source

Comparison of photodamage in non-pigmented and pigmented human skin equivalents exposed to repeated ultraviolet radiation to investigate the role of melanocytes in skin photoprotection

open access: yesFrontiers in Medicine
IntroductionDaily solar ultraviolet (UV) radiation has an important impact on skin health. Understanding the initial events of the UV-induced response is critical to prevent deleterious conditions.
Paola De Los Santos Gomez   +4 more
doaj   +1 more source

Transcriptome Analysis of the Breast Muscle of Xichuan Black-Bone Chickens Under Tyrosine Supplementation Revealed the Mechanism of Tyrosine-Induced Melanin Deposition

open access: yesFrontiers in Genetics, 2019
The Xichuan black-bone chicken, which is a rare local chicken species in China, is an important genetic resource of black-bone chickens. Tyrosine can affect melanin production, but the molecular mechanism underlying tyrosine-induced melanin deposition in
Donghua Li   +20 more
doaj   +1 more source

Deep Learning for Skin Lesion Classification [PDF]

open access: yesarXiv, 2017
Melanoma, a malignant form of skin cancer is very threatening to life. Diagnosis of melanoma at an earlier stage is highly needed as it has a very high cure rate. Benign and malignant forms of skin cancer can be detected by analyzing the lesions present on the surface of the skin using dermoscopic images.
arxiv  

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