Results 161 to 170 of about 48,156 (309)

Tumor diversity and evolution revealed through RADseq [PDF]

open access: yes, 2017
Altshuler   +66 more
core   +2 more sources

SOX10 Regulates Melanoma Metastasis Through the IRF1‐ITGA3/EphA2‐FAK Pathway

open access: yesCancer Science, EarlyView.
Although the subpopulation with invasiveness in melanoma shows MITFlow/AXLhigh, the underlying mechanisms remain unclear. In this study, we identified that the reduced expression of SOX10 promotes melanoma metastasis through the IRF1‐ITGA3/EphA2‐FAK pathway and highlight FAK inhibition as a potential therapeutic strategy.
Ryuya Kaminaka   +10 more
wiley   +1 more source

Melanocytic Nevus [PDF]

open access: yesEar, Nose & Throat Journal, 2006
openaire   +2 more sources

Organoid Models to Study Human Infectious Diseases

open access: yesCell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu   +4 more
wiley   +1 more source

Establishment and Validation of a C57BL/6J Mouse Model for Melasma

open access: yesCell Proliferation, EarlyView.
A melasma‐like mouse model was established in C57BL/6J mice using a combination of UVB irradiation, progesterone administration, and chronic psychological stress. This model replicates key clinical features and biomarker alterations observed in human melasma. Importantly, it is fundamentally distinct from UV‐induced post‐inflammatory hyperpigmentation (
Wenzhu Wang   +9 more
wiley   +1 more source

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