Results 171 to 180 of about 116,555 (410)
Poultry Science: The presence of a significant number of melanocytes in the ovary and follicular membrane of Silky Fowl suggests their potential involvement in follicle development.
Yurong Tai +7 more
doaj
Region of Interest Detection in Melanocytic Skin Tumor Whole Slide Images -- Nevus & Melanoma [PDF]
arXivAutomated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology may help us to reduce costs and increase the speed and accuracy of cancer diagnosis.
arxiv
Aetiology and treatment of epidermal depigmentory disorder in humans [PDF]
, 2012 The epidermal depigmentary trigger in humans at post-natal level may occur with the toxification of skin organ with the endogenously produced melanocytotoxic hydrogen peroxide and subsequent formation of hydrogen peroxide- melanolipoprotein conjugate ...
S. S. Sawhney
core +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Immune checkpoint inhibitors, such as antiPD1, revolutionized melanoma treatment. However, resistance and low response rates remain problems. Our goal was to pinpoint actionable biomarkers of resistance to anti‐PD1 treatment and verify therapeutic effectiveness in vivo.
Szonja Anna Kovács +13 more
wiley +1 more source
Artificial Intelligence-Based Triaging of Cutaneous Melanocytic Lesions [PDF]
arXivPathologists are facing an increasing workload due to a growing volume of cases and the need for more comprehensive diagnoses. Aiming to facilitate workload reduction and faster turnaround times, we developed an artificial intelligence (AI) model for triaging cutaneous melanocytic lesions based on whole slide images.
arxiv
Look past the cooperative eye hypothesis: reconsidering the evolution of human eye appearance
Biological Reviews, EarlyView.ABSTRACT The external appearance of the human eye has been prominently linked to the evolution of complex sociocognitive functions in our species. The cooperative eye hypothesis (CEH) proposes that human eyeballs, with their weakly expressed conjunctival and scleral pigmentation, are uniquely conspicuous and evolved under selective pressures to behave ...
Juan Olvido Perea‐García +2 more
wiley +1 more source
Identification of a Distal Enhancer That Regulates TGF‐β–Induced SNAI1 Expression
Cancer Science, EarlyView.In TGF‐β–stimulated cells, the activated Smad complex composed of Smad3 and Smad4 associates with the distal super enhancer region 2 (DSE2) and enhances its interaction with the SNAI1 proximal promoter, thus inducing SNAI1 expression. RREB1 regulates the basal activity of the enhancer but not its inducibility by TGF‐β.
Hao Fu +6 more
wiley +1 more source
In vivo assay for melanocyte lightening substances [PDF]
, 1966 Abba J. Kastin, Andrew V. Schally
openalex +1 more source
Role of the RAB27/SYTL Axis in Tumor Microenvironment Construction
Cancer Science, EarlyView.This review focuses on the role of the RAB27/SYTL axis in various cancer types associated with tumor microenvironment modifications. The importance of this pathway and the potential therapeutic strategies targeting vesicle production for the treatment of cancer are also discussed.
Miwa Tanaka, Takuro Nakamura
wiley +1 more source
Melasma: A clinicopathological study of 43 cases
Indian Journal of Pathology and Microbiology, 2009 Melasma is a symmetrical hypermelanosis of the exposed skin characterized by brown macules on the sun-exposed areas of the skin. The present study was carried out on 43 patients to analyze the correlation between histopathological features with clinical ...
Sarvjot Vermani +3 more
doaj