Results 191 to 200 of about 116,555 (410)

The Prognostic Significance of Tumoral Melanosis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Tumoral melanosis (TM) is a histological term to describe a nodular aggregation of macrophages containing melanin pigment (melanophages) that is devoid of viable melanocytes. It is most often identified in skin, where it may be appreciated clinically as a pigmented lesion; however, it can also be found in other organs such as lymph ...
Alison J. Potter, Peter M. Ferguson, Serigne N. Lo, Tasnia Ahmed, Robert V. Rawson, John F. Thompson, Georgina V. Long, Richard A. Scolyer   +7 more
wiley   +1 more source

The Pseudoinflammatory Pattern Revisited

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT In 1973, Dr. Martin C. Mihm, Jr. presented the finding that congenital melanocytic nevi, when viewed at low magnification, resemble superficial and deep perivascular dermatitis, forming the so‐called “pseudoinflammatory” pattern. One year earlier, Dr. Richard A.
Christopher R. Shea
wiley   +1 more source

On the Presence in Hog Hypothalamus of (β-Corticotropin Releasing Factor,α- and (β-Melanocyte Stimulating Hormones, Adrenocorticotropin, Lysine-Vasopressin and Oxytocin

, 1962
Roger Guillemin, Andrew V. Schally, H. S. Lipscomb, Richard N. Andersen, John M. Long   +4 more
openalex   +1 more source

m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade [PDF]

, 2019
Melanoma is one of the most deadly and therapy-resistant cancers. Here we show that N6-methyladenosine (m6A) mRNA demethylation by fat mass and obesity-associated protein (FTO) increases melanoma growth and decreases response to anti-PD-1 blockade ...
Aplin, Andrew E., Cui, Yan-Hong, Deng, Yu, He, Chuan, He, Yu-Ying, Hwang, Seungmin, Lu, Zhike, Park, Gayoung, Shah, Palak, Wei, Jiangbo, Yang, Seungwon   +10 more
core   +1 more source

Melanoma Diagnosis in the Mihm Era—And Beyond

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT During the illustrious career of Martin C. Mihm Jr., MD, the diagnosis of melanoma underwent significant changes, to which he made many contributions. In early descriptions, melanomas were fungating tumor masses that were obviously malignant, and highly lethal. In seminal work by Dr. Mihm and his mentor, Wallace H.
David E. Elder
wiley   +1 more source

From neural crest cells to melanocytes: cellular plasticity during development and beyond

Cellular and Molecular Life Sciences, 2019
N. Vandamme, G. Berx
semanticscholar   +1 more source

Grading Melanocytic Dysplasia: Updated Histopathologic Criteria

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dr. Martin C. Mihm, Jr.'s innovative work on the dysplastic nevus achieved a milestone in his chapter in the World Health Organisation Classification of Skin Tumours (WHO‐C). WHO‐C presents a dichotomous classification (high‐grade versus low‐grade dysplastic nevi) and a quantitative metric to assess melanocytic nuclear enlargement.
Christopher R. Shea, Victor G. Prieto, Catherine M. Shachaf, Scott R. Florell   +3 more
wiley   +1 more source

The Difference Between Polymyxin B and Polymyxin E in Causing Skin Hyerpigmentation

Frontiers in Pharmacology, 2021
Dongna Zou, Haitao Yu, Feifei Li
doaj   +1 more source

CTLA-4 A49G gene polymorphism is not associated with vitiligo in South Indian population

Indian Journal of Dermatology, 2010
Background: Vitiligo or leukoderma is a chronic skin condition that causes loss of pigment due to destruction of melanocytes, resulting in irregular pale patches of skin.
Deeba Farha, Syed Rabbani, Quareen Jariya, Waheed M, Jamil Kaiser, Rao Hanmanth   +5 more
doaj  

Vitiligo Review: etiopathogenesis, diagnosis and treatment

Quality in Sport
Introduction and purpose:This review is intended for healthcare professionals, including dermatologists, primary care physicians, and researchers, who seek a comprehensive understanding of vitiligo. It is also relevant for patients and their families to
Aleksandra Witek, Jakub Parys, Agnieszka Mikosińska, Martyna Kaźmierczak, Maciej Mossakowski, Patrycja Kałuziak, Marta Jajczak, Mateusz Litwin, Stanisław Jesionek, RAfał Bieś   +9 more
doaj   +1 more source