Results 111 to 120 of about 933,936 (328)

35 | Real-world outcomes of targeted therapy in stage IV melanoma after relapse on adjuvant dabrafenib and trametinib: insights from a single-center cohort

Dermatology Reports
Background: Adjuvant dabrafenib and trametinib (DT) reduce relapse risk in stage III BRAF-mutant melanoma, but data on recurrence patterns and management after relapse remain scarce.
Italian Melanoma Intergroup
doaj   +1 more source

miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy

Journal of Experimental & Clinical Cancer Research, 2019
Background Mucosal melanoma with poor prognosis is a common histopathologic subtype of melanoma among Chinese and other Asian peoples. Regulated microRNAs (miRNAs) have been reported as oncogenes or tumour suppressors in melanoma.
Huan Tang, Meng Ma, Jie Dai, Chuanliang Cui, Lu Si, Xinan Sheng, Zhihong Chi, Longwen Xu, Sifan Yu, Tianxiao Xu, Junya Yan, Huan Yu, Lu Yang, Yan Kong, Jun Guo   +14 more
doaj   +1 more source

Melanoma [PDF]

Journal of the National Comprehensive Cancer Network, 2012
Daniel G, Coit, Robert, Andtbacka, Christopher J, Anker, Christopher K, Bichakjian, William E, Carson, Adil, Daud, Raza A, Dilawari, Dominick, Dimaio, Valerie, Guild, Allan C, Halpern, F Stephen, Hodi, Mark C, Kelley, Nikhil I, Khushalani, Ragini R, Kudchadkar, Julie R, Lange, Anne, Lind, Mary C, Martini, Anthony J, Olszanski, Scott K, Pruitt, Merrick I, Ross, Susan M, Swetter, Kenneth K, Tanabe, John A, Thompson, Vijay, Trisal, Marshall M, Urist   +24 more
openaire   +2 more sources

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

27 | Real-world data for malignant melanoma stage II adjuvant therapy

Dermatology Reports
Background: Malignant melanoma (MM) is an aggressive cancer with high metastatic potential from early stages. Stage IIB/C MM shows overall survival lower than stage IIIA, with high recurrence risk. Recently, 1-year pembrolizumab or nivolumab was approved
Italian Melanoma Intergroup
doaj   +1 more source

Data from Inducible Nitric Oxide Synthase Drives mTOR Pathway Activation and Proliferation of Human Melanoma by Reversible Nitrosylation of TSC2

, 2023
Esther López-Rivera, Padmini Jayaraman, Falguni Parikh, Michael A. Davies, Sühendan Ekmekçioglu, Sudeh Izadmehr, Denái R. Milton, Jerry E. Chipuk, Elizabeth A. Grimm, Yeriel Estrada, Julio A. Aguirre‐Ghiso, Andrew G. Sikora   +11 more
openalex   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

26 | Tumor size may predict early response to sonidegib in locally-advanced basal cell carcinoma: clinical and histopathological correlates from a monocentric case series

Dermatology Reports
Background: Sonic Hedgehog (SHH) inhibitors, including sonidegib, have emerged as effective therapies for locally advanced basal cell carcinoma (LA-BCC). However, variability in clinical response has been observed.
Italian Melanoma Intergroup
doaj   +1 more source

Supplemental Figures and Tables from Notch4 Signaling Induces a Mesenchymal–Epithelial–like Transition in Melanoma Cells to Suppress Malignant Behaviors

, 2023
Ehsan Bonyadi Rad, Heinz Hammerlindl, Christian Wels, Ulrich Popper, Dinoop Ravindran Menon, Heimo Breiteneder, Melitta Kitzwoegerer, Christine Häfner, Meenhard Herlyn, Helmut Bergler, Helmut Schaider   +10 more
openalex   +1 more source

COVID‐19 Vaccination is not Associated with the Development of Idiopathic Inflammatory Myositis in U.S. Veterans

Arthritis Care &Research, Accepted Article.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US Veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández, Naomi Schlesinger, Jorge Rojas, Jessica A. Walsh, Tawnie J Braaten, Gary A Kunkel, Makoto Jones, Brian C Sauer, Julio Facelli, Grant W. Cannon, Dorota Lebiedz‐Odrobina   +10 more
wiley   +1 more source