Results 21 to 30 of about 458,085 (304)

WIPI1, BAG1 and PEX3 autophagy-related genes are relevant melanoma markers [PDF]

, 2018
ROS and oxidative stress may promote autophagy; on the other hand, autophagy may help reduce oxidative damages. According to the known interplay of ROS, autophagy, and melanoma onset, we hypothesized that autophagy-related genes (ARGs) may represent ...
D’Arcangelo, Daniela, Facchiano, Antonio, Facchiano, Francesco, Giampietri, Claudia, Muscio, Mario, Scatozza, Francesca   +5 more
core   +1 more source

Pathological impact and medical applications of electromagnetic field on melanoma: A focused review

Frontiers in Oncology, 2022
Electromagnetic Field (EMF) influences melanoma in various ways. EMF can be classified into extremely low-frequency electromagnetic field, low-frequency magnetic field, static moderate magnetic field, strong electromagnetic field, alternating magnetic ...
Yunxiao Duan, Xiaowen Wu, Ziqi Gong, Qian Guo, Yan Kong   +4 more
doaj   +1 more source

Computer-Aided Decision Support for Melanoma Detection Applied on Melanocytic and Nonmelanocytic Skin Lesions: A Comparison of Two Systems Based on Automatic Analysis of Dermoscopic Images [PDF]

BioMed Research International, vol. 2015, Article ID 579282, 8 pages, 2015, 2016
Commercially available clinical decision support systems (CDSSs) for skin cancer have been designed for the detection of melanoma only. Correct use of the systems requires expert knowledge, hampering their utility for nonexperts. Furthermore, there are no systems to detect other common skin cancer types, that is, nonmelanoma skin cancer (NMSC).
arxiv   +1 more source

Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules [PDF]

, 2018
Background: Microenvironment cues involved in melanoma progression are largely unknown. Melanoma is highly influenced in its aggressive phenotype by the changes it determinates in its microenvironment, such as pH decrease, in turn influencing cancer cell
A Albini, A Lardner, Alessandra Carè, AR Hess, Bok Hong, C Coscia, Carla Raggi, CC Jiang, CP Lai, Cristiana Zanetti, D Hanahan, E Alegre, E Willms, EK Rofstad, Elin J Ekström, Elisabetta Pizzi, Fabrizio Mattei, Federica Felicetti, Federica Fratini, G Helmlinger, G Raposo, H Mizuno, H Peinado, I Lazar, I Parolini, IF Robey, Isabella Parolini, J Kowal, J Lotvall, J Niu, J Skog, J Webber, Jessica Lamberti, JL Hood, JL Hood, JL Wike-Hooley, JM Graham, JR Knutson, K Al-Nedawi, Katia Fecchi, Luca Fantozzi, Luca Pasquini, M Colombo, M Logozzi, Massimo Sanchez, Massimo Sargiacomo, MR Muhsin-Sharafaldine, N Raghunand, O WARBURG, P Vaupel, R Valenti, RE Moellering, Rossella Puglisi, S Dror, S Dutta, S Peppicelli, SK Huang, Stefania D’Atri, T Fiaschi, T Fukamachi, T Groot Kormelink, T Kobayashi, V Estrella, V Pospichalova, V Vukovic, XY Yam, Y Ishihama, Zaira Boussadia   +67 more
core   +10 more sources

miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy

Journal of Experimental & Clinical Cancer Research, 2019
Background Mucosal melanoma with poor prognosis is a common histopathologic subtype of melanoma among Chinese and other Asian peoples. Regulated microRNAs (miRNAs) have been reported as oncogenes or tumour suppressors in melanoma.
Huan Tang, Meng Ma, Jie Dai, Chuanliang Cui, Lu Si, Xinan Sheng, Zhihong Chi, Longwen Xu, Sifan Yu, Tianxiao Xu, Junya Yan, Huan Yu, Lu Yang, Yan Kong, Jun Guo   +14 more
doaj   +1 more source

Non melanoma skin cancer pathogenesis overview [PDF]

, 2018
(1)Background: Non-melanoma skin cancer is the most frequently diagnosed cancer in humans. The process of skin carcinogenesis is still not fully understood.
Bottoni Ugo, Cantisani Carmen, Didona Dario, Paolino Giovanni   +3 more
core   +1 more source

Classification of the tumor immune microenvironment and associations with outcomes in patients with metastatic melanoma treated with immunotherapies

Journal for ImmunoTherapy of Cancer, 2023
Background Tumor microenvironment (TME) characteristics are potential biomarkers of response to immune checkpoint inhibitors in metastatic melanoma.
Ines Pires da Silva, Richard A Scolyer, Georgina Long, Matteo S Carlino, Ismael A Vergara, James S Wilmott, Serigne N Lo, Tuba N Gide, Alexander Maxwell Menzies, Nurudeen A Adegoke, Yizhe Mao, Camelia Quek, Ellis Patrick   +12 more
doaj   +1 more source

Extended Feature Space-Based Automatic Melanoma Detection System [PDF]

arXiv, 2022
Melanoma is the deadliest form of skin cancer. Uncontrollable growth of melanocytes leads to melanoma. Melanoma has been growing wildly in the last few decades. In recent years, the detection of melanoma using image processing techniques has become a dominant research field.
arxiv  

Pre-clinical modeling of cutaneous melanoma

Nature Communications, 2020
Despite the new targeted and immunotherapies for metastatic melanoma, several patients show therapeutic plateau. Here, the authors review the current pre-clinical models of cutaneous melanoma and discuss their strengths and limitations that may help with
Vito W. Rebecca, Rajasekharan Somasundaram, Meenhard Herlyn   +2 more
doaj   +1 more source

Combination immunotherapy induces distinct T-cell repertoire responses when administered to patients with different malignancies. [PDF]

, 2020
BackgroundCTLA-4 blockade with ipilimumab is Food and Drug Administration-approved for melanoma as a monotherapy and has been shown to modulate the circulating T-cell repertoire.
Cham, Jason, Fong, Grant, Fong, Lawrence, He, Tao, Kwek, Serena, Oh, David Y, Paciorek, Alan, Zhang, Li   +7 more
core   +1 more source