Results 81 to 90 of about 552,068 (289)

32 | Tebentafusp in metastatic uveal melanoma: 3 years of real world data and insights from liquid biopsy

Dermatology Reports
Background: Real world data are needed to optimize the use of Tebentafusp, the first agent improving the overall survival in metastatic uveal melanoma (mUM) patients even if progressive disease (PD) is the best response. Methods: Baseline clinical data,
Italian Melanoma Intergroup
doaj   +1 more source

Management of in‐transit melanoma metastases: a review [PDF]

, 2018
Emilia Nan Tie, Michael A. Henderson, David Gyorki   +2 more
openalex   +1 more source

Simultaneous blocking of the pan‐RAF and S100B pathways as a synergistic therapeutic strategy against malignant melanoma [PDF]

, 2020
Ke‐Jia Wu, Shih‐Hsin Ho, Wu Chun, Huimin Wang, Dik‐Lung Ma, Chung‐Hang Leung   +5 more
openalex   +1 more source

Uveal Melanoma [PDF]

Cancers, 2019
Uveal melanoma (UM) is among the best characterized solid tumors [...]
openaire   +2 more sources

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

35 | Real-world outcomes of targeted therapy in stage IV melanoma after relapse on adjuvant dabrafenib and trametinib: insights from a single-center cohort

Dermatology Reports
Background: Adjuvant dabrafenib and trametinib (DT) reduce relapse risk in stage III BRAF-mutant melanoma, but data on recurrence patterns and management after relapse remain scarce.
Italian Melanoma Intergroup
doaj   +1 more source

miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy

Journal of Experimental & Clinical Cancer Research, 2019
Background Mucosal melanoma with poor prognosis is a common histopathologic subtype of melanoma among Chinese and other Asian peoples. Regulated microRNAs (miRNAs) have been reported as oncogenes or tumour suppressors in melanoma.
Huan Tang, Meng Ma, Jie Dai, Chuanliang Cui, Lu Si, Xinan Sheng, Zhihong Chi, Longwen Xu, Sifan Yu, Tianxiao Xu, Junya Yan, Huan Yu, Lu Yang, Yan Kong, Jun Guo   +14 more
doaj   +1 more source

Ex vivo mapping of enhancer networks that define the transcriptional program driving melanoma metastasis [PDF]

, 2023
Veronica Manicardi, Mila Gugnoni, Elisabetta Sauta, Benedetta Donati, Emanuele Vitale, Federica Torricelli, Gloria Manzotti, Simonetta Piana, Caterina Longo, Francesco Ghini, Alessia Ciarrocchi   +10 more
openalex   +1 more source

Melanoma [PDF]

Journal of the National Comprehensive Cancer Network, 2012
Daniel G, Coit, Robert, Andtbacka, Christopher J, Anker, Christopher K, Bichakjian, William E, Carson, Adil, Daud, Raza A, Dilawari, Dominick, Dimaio, Valerie, Guild, Allan C, Halpern, F Stephen, Hodi, Mark C, Kelley, Nikhil I, Khushalani, Ragini R, Kudchadkar, Julie R, Lange, Anne, Lind, Mary C, Martini, Anthony J, Olszanski, Scott K, Pruitt, Merrick I, Ross, Susan M, Swetter, Kenneth K, Tanabe, John A, Thompson, Vijay, Trisal, Marshall M, Urist   +24 more
openaire   +2 more sources

Liquid Crystalline Inverted Lipid Phases and Reverse Micelles in Drug Delivery: From Molecular Design to Therapeutic Potential

Advanced Functional Materials, EarlyView.
Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu, Mulazim Hussain Asim, Soheil Haddadzadegan, Andreas Bernkop‐Schnürch   +3 more
wiley   +1 more source