Results 101 to 110 of about 11,542 (237)
The effects of a HEV‐filtering contact lens on the brightness of natural images
Abstract Purpose Yellow filters, including high‐energy‐visible (HEV) filtering lenses, have been thought to increase the subjective brightness of real‐world scenes, but laboratory results are mixed. This study used a brightness matching technique modified to present natural images using a broad spectrum of wavelengths: a visibly clear control contact ...
Billy R. Hammond +6 more
wiley +1 more source
Visual Responses in Mice Lacking Critical Components of All Known Retinal Phototransduction Cascades [PDF]
The mammalian visual system relies upon light detection by outer-retinal rod/cone photoreceptors and melanopsin-expressing retinal ganglion cells. Gnat1(-/-); Cnga3(-/-); Opn4(-/-) mice lack critical elements of each of these photoreceptive mechanisms ...
Allen, AE +4 more
core
In Synch but Not in Step: Circadian Clock Circuits Regulating Plasticity in Daily Rhythms [PDF]
The suprachiasmatic nucleus (SCN) is a network of neural oscillators that program daily rhythms in mammalian behavior and physiology. Over the last decade much has been learned about how SCN clock neurons coordinate together in time and space to form a ...
Evans, Jennifer A., Gorman, M. R.
core +2 more sources
The melanopsin system consists of retinal ganglion cells containing the photopigment melanospin, which are directly activated by light in the absence of inputs from the photoreceptors. These intrinsically photosensitive retinal ganglion cells (ipRGCs) detect environmental brightness; combine their direct, melanospin-triggered photoresponses with ...
openaire +2 more sources
Circadian disruption is a potential carcinogen, but the impact of environmental carcinogens on circadian rhythms is unclear. Here we evaluated the impact of chronic UVB exposure with environmental‐ and genetic‐induced circadian disruption on mouse rhythmic locomotor activity and clock gene expression. Created in BioRender. Cone, S.
Adam J. Greer +6 more
wiley +1 more source
Blue light activates pulvinar nuclei in longstanding idiopathic photophobia: A case report
Numerous pathologies can contribute to photophobia. When considering light transduction alone, photophobia may be triggered through melanopsin pathways (non-image forming), rod and cone pathways (image-forming), or some combination of the two.
Athanasios Panorgias +4 more
doaj +1 more source
The Effects of Food on Circadian Rhythm: A Comprehensive Review
(a) Light signals are received by the retina and transmitted to the suprachiasmatic nucleus (SCN), the master circadian clock, which synchronizes peripheral clocks in metabolic tissues via neural and humoral pathways (e.g., cortisol). (b) The molecular clock is governed by a transcriptional‐translational feedback loop.
Jiazheng Hu +7 more
wiley +1 more source
An insight into light as a chronobiological therapy in affective disorders [PDF]
The field of chronobiology has vastly expanded over the past few decades, bringing together research from the fields of circadian rhythms and sleep. The importance of the environmental day–night cycle on our health is becoming increasingly evident as we ...
Atkinson, Lynsey A. +3 more
core +3 more sources
Dreamy Dwellings: How the Sleep Environment Affects Sleep Health in Adults—A Narrative Review
ABSTRACT Sufficient high‐quality, well‐timed sleep is essential to health and physical, cognitive and emotional functions. Historically, environmental factors such as threats from other beings have likely constrained sleep. Newer sources of sleep disruption include modern work schedules, climate change, light pollution and noise pollution.
Gregory David Maxwell Potter +5 more
wiley +1 more source
DNA aptamers can bind specifically to biomolecules to modify their function, potentially making them ideal oligonucleotide therapeutics. Herein, we screened for DNA aptamer of melanopsin (OPN4), a blue-light photopigment in the retina, which plays a key ...
Kazuo Nakazawa +7 more
doaj +1 more source

