Results 101 to 110 of about 11,542 (237)

The effects of a HEV‐filtering contact lens on the brightness of natural images

open access: yesOphthalmic and Physiological Optics, Volume 45, Issue 7, Page 1801-1810, November 2025.
Abstract Purpose Yellow filters, including high‐energy‐visible (HEV) filtering lenses, have been thought to increase the subjective brightness of real‐world scenes, but laboratory results are mixed. This study used a brightness matching technique modified to present natural images using a broad spectrum of wavelengths: a visibly clear control contact ...
Billy R. Hammond   +6 more
wiley   +1 more source

Visual Responses in Mice Lacking Critical Components of All Known Retinal Phototransduction Cascades [PDF]

open access: yes, 2010
The mammalian visual system relies upon light detection by outer-retinal rod/cone photoreceptors and melanopsin-expressing retinal ganglion cells. Gnat1(-/-); Cnga3(-/-); Opn4(-/-) mice lack critical elements of each of these photoreceptive mechanisms ...
Allen, AE   +4 more
core  

In Synch but Not in Step: Circadian Clock Circuits Regulating Plasticity in Daily Rhythms [PDF]

open access: yes, 2016
The suprachiasmatic nucleus (SCN) is a network of neural oscillators that program daily rhythms in mammalian behavior and physiology. Over the last decade much has been learned about how SCN clock neurons coordinate together in time and space to form a ...
Evans, Jennifer A., Gorman, M. R.
core   +2 more sources

The melanopsin system [PDF]

open access: yesNeurology, 2011
The melanopsin system consists of retinal ganglion cells containing the photopigment melanospin, which are directly activated by light in the absence of inputs from the photoreceptors. These intrinsically photosensitive retinal ganglion cells (ipRGCs) detect environmental brightness; combine their direct, melanospin-triggered photoresponses with ...
openaire   +2 more sources

Long‐term sub‐erythemal UVB exposure does not impact circadian rhythms in mice under standard and rotating shift light conditions

open access: yesPhotochemistry and Photobiology, Volume 101, Issue 6, Page 1429-1442, November/December 2025.
Circadian disruption is a potential carcinogen, but the impact of environmental carcinogens on circadian rhythms is unclear. Here we evaluated the impact of chronic UVB exposure with environmental‐ and genetic‐induced circadian disruption on mouse rhythmic locomotor activity and clock gene expression. Created in BioRender. Cone, S.
Adam J. Greer   +6 more
wiley   +1 more source

Blue light activates pulvinar nuclei in longstanding idiopathic photophobia: A case report

open access: yesNeuroImage: Clinical, 2019
Numerous pathologies can contribute to photophobia. When considering light transduction alone, photophobia may be triggered through melanopsin pathways (non-image forming), rod and cone pathways (image-forming), or some combination of the two.
Athanasios Panorgias   +4 more
doaj   +1 more source

The Effects of Food on Circadian Rhythm: A Comprehensive Review

open access: yeseFood, Volume 6, Issue 5, October 2025.
(a) Light signals are received by the retina and transmitted to the suprachiasmatic nucleus (SCN), the master circadian clock, which synchronizes peripheral clocks in metabolic tissues via neural and humoral pathways (e.g., cortisol). (b) The molecular clock is governed by a transcriptional‐translational feedback loop.
Jiazheng Hu   +7 more
wiley   +1 more source

An insight into light as a chronobiological therapy in affective disorders [PDF]

open access: yes, 2014
The field of chronobiology has vastly expanded over the past few decades, bringing together research from the fields of circadian rhythms and sleep. The importance of the environmental day–night cycle on our health is becoming increasingly evident as we ...
Atkinson, Lynsey A.   +3 more
core   +3 more sources

Dreamy Dwellings: How the Sleep Environment Affects Sleep Health in Adults—A Narrative Review

open access: yesLifestyle Medicine, Volume 6, Issue 4, October 2025.
ABSTRACT Sufficient high‐quality, well‐timed sleep is essential to health and physical, cognitive and emotional functions. Historically, environmental factors such as threats from other beings have likely constrained sleep. Newer sources of sleep disruption include modern work schedules, climate change, light pollution and noise pollution.
Gregory David Maxwell Potter   +5 more
wiley   +1 more source

Melanopsin DNA aptamers can regulate input signals of mammalian circadian rhythms by altering the phase of the molecular clock

open access: yesFrontiers in Neuroscience
DNA aptamers can bind specifically to biomolecules to modify their function, potentially making them ideal oligonucleotide therapeutics. Herein, we screened for DNA aptamer of melanopsin (OPN4), a blue-light photopigment in the retina, which plays a key ...
Kazuo Nakazawa   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy