Results 111 to 120 of about 103,843 (303)

Melatonin decreases excessive polyspermy for single oocyte in pigs through the MT2 receptor

Scientific Reports
Melatonin supplementation during in vitro maturation (IVM) improves porcine oocyte maturation and embryonic development by exerting antioxidative effects.
Jing-Tao Sun, Jia-Hui Liu, Lu Zhao, Hang-Yu Chen, Ren-Fei Wang, Yong-Jia Li, Xiao-Gang Weng, Zhong-Hua Liu, Qian Shen, Bao-Xiu Zhang, Jun-Xue Jin   +10 more
doaj   +1 more source

Morning Plasma Melatonin Differences in Autism: Beyond the Impact of Pineal Gland Volume

Frontiers in Psychiatry, 2019
While low plasma melatonin, a neuro-hormone synthesized in the pineal gland, has been frequently associated with autism, our understanding of the mechanisms behind it have remained unclear.
Anna Maruani, Anna Maruani, Guillaume Dumas, Anita Beggiato, Anita Beggiato, Nicolas Traut, Hugo Peyre, Alicia Cohen-Freoua, Frédérique Amsellem, Frédérique Amsellem, Monique Elmaleh, David Germanaud, David Germanaud, Jean-Marie Launay, Thomas Bourgeron, Roberto Toro, Richard Delorme, Richard Delorme   +17 more
doaj   +1 more source

Effect of Melatonin and Analogues on Corneal Wound Healing: Involvement of Mt2 Melatonin Receptor

, 2015
Purpose: We have investigated the effect of melatonin and its analogues on rabbit corneal epithelial wound healing. Methods: New Zealand rabbits were anaesthetised and wounds were made by placing Whatman paper discs soaked in n-heptanol on the cornea ...
Alarma Estrany, Pilar, Carracedo Rodríguez, Juan Gonzalo, Crooke Álvarez, Almudena, Peláez García, María Teresa, Peral Cerda, María Asunción, Guzmán Aránguez, Ana Isabel, Mediero Muñoz, Aránzazu, Pintor Just, Jesús Jerónimo   +7 more
core   +1 more source

Magyarországi meggyfajták melatonin tartalmának összehasonlító elemzése

, 2014
Magyarországi meggyfajták melatonin tartalmának összehasonlító elemzése.gjVegyészMSc ...
Samók, Zsolt
core  

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Gyógyhatású növények melatonin tartalmának összehasonlító elemzése

, 2015
Gyógyhatású növények melatonin tartalmának összehasonlító elemzésegjVegyész (MSc)MSc ...
Samók, Zsolt
core  

Incident low‐dose quetiapine use in adults newly diagnosed with depression in primary care: A nationwide register‐based study

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate the incidence of low‐dose quetiapine initiation and associated factors in adults newly diagnosed with depression in primary care. Methods We obtained medication dispensing records, primary and secondary care diagnoses and employment status for antipsychotic‐naïve individuals aged 16–65 newly diagnosed with ...
Laura Purra, Heidi Taipale, Miia Tiihonen, Markku Lähteenvuo, Jari Tiihonen, Aleksi Hamina   +5 more
wiley   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu, Zeynep Betül Sarı, Muhammed Emin Sarı, Erdi Can Aytar   +3 more
wiley   +1 more source

Melatonin as an anti-stress signal: effects on an acute stress model and direct actions on interrenal tissue in goldfish

Frontiers in Endocrinology
BackgroundMelatonin is a key hormone in regulation of circadian rhythms, and involved in many rhythmic functions, such as feeding and locomotor activity. Melatonin reportedly counteracts stress responses in many vertebrates, including fish.
Clara Azpeleta, Clara Azpeleta, Mª Jesús Delgado, Juriaan R. Metz, Gert Flik, Nuria de Pedro   +5 more
doaj   +1 more source