Results 91 to 100 of about 92,984 (317)

Effects of oral administration of melatonin on bone metabolism

open access: yes, 2001
P(論文)We have recently demonstrated that melatonin stimulates proliferation and type I collagen synthesis of normal human osteoblastic cells in vitro. We have further shown that daily I.P.
政所, 明弘   +9 more
core  

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

open access: yesFood Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima   +4 more
wiley   +1 more source

Morning Plasma Melatonin Differences in Autism: Beyond the Impact of Pineal Gland Volume

open access: yesFrontiers in Psychiatry, 2019
While low plasma melatonin, a neuro-hormone synthesized in the pineal gland, has been frequently associated with autism, our understanding of the mechanisms behind it have remained unclear.
Anna Maruani   +17 more
doaj   +1 more source

Melatonin-induced increases in Per1 and Per2 mRNAs are blocked by E-box decoy ODN.

open access: yes, 2016
Pre-treatment of SCN slices with E-box decoy ODN (1 μM), blocks the melatonin-induced increase in Per1 (A) and Per2 (B) transcripts after 120 min. qPCR data are shown as percent change of relative mRNA levels compared to control ± SEM, n = 3/condition (**
Martha U. Gillette (242517)   +2 more
core   +1 more source

Specificity and nanomolar potency of melatonin on G-protein coupled melatonin MT1 and MT2 receptors expressed in HEK-293T human embryo kidney cells [PDF]

open access: yes, 2019
This is a pre-registered study, i.e. a study whose hypotheses and experiments designed to address these hypotheses has been deposited in a database before starting the experiments.
Alkozi, Hanan Awad   +8 more
core   +1 more source

Roles of histone lysine methylation in neurodevelopment and related disorders

open access: yesIbrain, EarlyView.
This graphical abstract centers on the theme of dynamic balance and systematically outlines the role of histone lysine methylation in neurodevelopment and related disorders. The figure first presents two key classes of regulators that control this balance—“writers” and “erasers”—and then indicates how interactions among different epigenetic ...
Yun Chen   +3 more
wiley   +1 more source

Magyarországi meggyfajták melatonin tartalmának összehasonlító elemzése

open access: yes, 2014
Magyarországi meggyfajták melatonin tartalmának összehasonlító elemzése.gjVegyészMSc ...
Samók, Zsolt
core  

Effect of Melatonin and Analogues on Corneal Wound Healing: Involvement of Mt2 Melatonin Receptor

open access: yes, 2015
Purpose: We have investigated the effect of melatonin and its analogues on rabbit corneal epithelial wound healing. Methods: New Zealand rabbits were anaesthetised and wounds were made by placing Whatman paper discs soaked in n-heptanol on the cornea ...
Alarma Estrany, Pilar   +7 more
core   +1 more source

Engineered Bacillus subtilis regulates intestinal barrier in ETEC K88‐infected piglets and modulates miR‐1250‐5p/NFκB pathway in IPEC‐J2

open access: yesiMetaOmics, EarlyView.
Upon enterotoxigenic Escherichia coli (ETEC) K88 infection, intestinal barrier function is disrupted with compromised tight junctions, accompanied by an exacerbated inflammatory response, proliferation of pathogenic Escherichia, and depletion of beneficial Lactobacillus paralimentarius.
Chaoyue Wen   +11 more
wiley   +1 more source

The role of Toll-like receptor 4 (TLR-4) in wine-induced cardioprotection

open access: yes, 2012
Includes abstract.Includes bibliographical references.Moderate and chronic consumption of red wine confers cardioprotection. Melatonin, present in wine, may contribute to this cardioprotective effect. Melatonin confers cardioprotection via the activation
Albertyn, Zulfah
core  

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