Results 101 to 110 of about 108,758 (309)

Natural melatonin fluctuation and its minimally invasive simulation in the zebra finch [PDF]

open access: yesPeerJ, 2016
Melatonin is a key hormone in the regulation of circadian rhythms of vertebrates, including songbirds. Understanding diurnal melatonin fluctuations and being able to reverse or simulate natural melatonin levels are critical to investigating the influence
Susanne Seltmann   +3 more
doaj   +2 more sources

Can melatonin reduce the severity of COVID-19 pandemic?

open access: yesInternational Reviews of Immunology, 2020
The current COVID-19 pandemic is one of the most devastating events in recent history. The virus causes relatively minor damage to young, healthy populations, imposing life-threatening danger to the elderly and people with diseases of chronic ...
Alexander M. Shneider   +2 more
semanticscholar   +1 more source

Melatonin, Melatonin Receptors and Melanophores: A Moving Story [PDF]

open access: yesPigment Cell Research, 2004
Melatonin (5‐methoxy N‐acetyltryptamine) is a hormone synthesized and released from the pineal gland at night, which acts on specific high affinity G‐protein coupled receptors to regulate various aspects of physiology and behaviour, including circadian and seasonal responses, and some retinal, cardiovascular and immunological functions.
Sugden, D   +3 more
openaire   +2 more sources

Melatonin-Induced Plant Tolerance to Heavy Metal Stress

open access: yes, 2023
The prime goal of this chapter is to provide the latest information regarding the role of melatonin in alleviation of heavy metal in crop plants and to encourage botanists to further evaluate the tolerance mechanisms of melatonin in plants. Consequently,
L. Barbanti   +6 more
core   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

open access: yesAdvanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan   +14 more
wiley   +1 more source

The role of melatonin in the light of current knowledge

open access: yes, 2016
Recent studies have shed new light on the role of melatonin. Local tissue synthesis has been investigated. A special system responsible for the synthesis and metabolism of melatonin has developed in the human skin.
Ewa Trznadel-Grodzka   +3 more
core   +1 more source

Melatonin Mitigates Doxorubicin‐Induced Cardiotoxicity by Targeting the USP18/PKM2 Axis Without Compromising Antitumor Efficacy

open access: yesAdvanced Science, EarlyView.
Melatonin engages MT1/MT2 receptors to suppress STAT1‐driven USP18 upregulation, thereby redirecting PKM2 ubiquitination from K33‐linked autophagic degradation toward K27‐linked nuclear translocation. This prevents PKM2‐mediated proinflammatory gene expression in the heart, alleviating doxorubicin‐induced cardiotoxicity without compromising antitumor ...
Zhenyu Feng   +10 more
wiley   +1 more source

Network Pharmacology of the Phytochemical Content of Sunflower Seed (Helianthus annuus L.) Extract from LC-MS on Wound-Healing Activity and the In Vitro Wound Scratch Assay

open access: yesPlants
Sunflower seeds have been reported to be a healthy natural source of polyphenols. This study aimed to explore the mechanisms of potential compounds in sunflower seed extract involved in wound healing; major compounds were investigated through network ...
Juthamat Ratha   +7 more
doaj   +1 more source

Engineered Chiral Probiotics Ameliorate MASH via Gut–Liver Axis

open access: yesAdvanced Science, EarlyView.
A chiral gold nanozyme was coated onto the gut commensal bacterium Faecalibacterium duncaniae (F. duncaniae) to create an engineered probiotic. In mouse models of MASH, this orally administered living therapeutic protected the bacterium against oxidative stress, enhanced its gut colonization, reversed steatosis, inflammation, and fibrosis, and improved
Jing Chen   +12 more
wiley   +1 more source

The Effect of Melatonin Adjuvant on Cognitive Function and Melatonin Levels in Schizophrenia Patients [PDF]

open access: yes
Background: Schizophrenia is an important and serious mental disorder. It has been studied that serum melatonin levels were significantly decreased in schizophrenia patients.
Andi Jayalangkara Tanra   +7 more
core   +2 more sources

Home - About - Disclaimer - Privacy