Results 121 to 130 of about 227,315 (399)

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

open access: yesEuropean Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard   +29 more
wiley   +1 more source

Photoperiod influences the development and the expression of personality traits and social behaviour in wild cavies (Cavia aperea)

open access: yesEthology, Volume 129, Issue 1, Page 33-46, January 2023., 2023
Seasonal variation in temperature and food abundance strongly influences life history and behaviour. For animals living in non‐tropical regions, seasonal variation can be reliably predicted by photoperiod and be used for plastic adjustments. Here, we tested if maternal behaviour of the precocial cavy (Cavia aperea) responds to photoperiodic cues and ...
Anja Guenther, Fritz Trillmich
wiley   +1 more source

Melatonin Modulates the GABAergic Response in Cultured Rat Hippocampal Neurons

open access: yesJournal of Pharmacological Sciences, 2012
In the present study, we investigated the effect of melatonin on the GABA-induced current (IGABA) and GABAergic miniature inhibitory postsynaptic currents (mIPSCs) in cultured rat hippocampal neurons using the whole-cell patch-clamp technique.
Xin-Ping Cheng   +3 more
doaj  

Morning Plasma Melatonin Differences in Autism: Beyond the Impact of Pineal Gland Volume

open access: yesFrontiers in Psychiatry, 2019
While low plasma melatonin, a neuro-hormone synthesized in the pineal gland, has been frequently associated with autism, our understanding of the mechanisms behind it have remained unclear.
Anna Maruani   +17 more
doaj   +1 more source

Melatonin as a potential therapy for sepsis : a phase I dose escalation study and an ex vivo whole blood model under conditions of sepsis [PDF]

open access: yes, 2014
This article is protected by copyright. All rights reserved. This study was funded by the Chief Scientist Office, NHS Scotland. We would like to thank all the volunteers who gave up their time and blood to take part in the study and the data monitoring ...
Allen, Lee   +5 more
core   +1 more source

Exploring Proteomic and Metabolomic Interactions in a Yeast Consortium Designed to Enhance Bioactive Compounds in Wine Fermentations

open access: yesFood Frontiers, EarlyView.
A consortium of Saccharomyces species enhanced the production of bioactive molecules Proteomic and metabolomic data indicated that the presence of a competitive strain accelerated the growth rate of S. cerevisiae and increase the synthesis of indolic compounds in S.
Andrés Planells‐Cárcel   +4 more
wiley   +1 more source

Effect of Several Nutrients and Environmental Conditions on Intracellular Melatonin Synthesis in Saccharomyces cerevisiae

open access: yesMicroorganisms, 2020
Melatonin is a bioactive compound that is present in fermented beverages and has been described to be synthesized by yeast during alcoholic fermentation.
María Ángeles Morcillo-Parra   +3 more
doaj   +1 more source

The influence of season, photoperiod, and pineal melatonin on immune function. [PDF]

open access: yes, 1995
In addition to the well-documented seasonal cycles of mating and birth, there are also significant seasonal cycles of illness and death among many animal populations.
Demas, G   +3 more
core   +1 more source

Tolerance to Stress Combination in Tomato Plants: New Insights in the Protective Role of Melatonin

open access: yesMolecules, 2018
Abiotic stresses such as drought, heat or salinity are major causes of yield loss worldwide. Recent studies have revealed that the acclimation of plants to a combination of different environmental stresses is unique and therefore cannot be directly ...
V. Martínez   +9 more
semanticscholar   +1 more source

Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]

open access: yes, 2020
Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core   +1 more source

Home - About - Disclaimer - Privacy