Results 131 to 140 of about 227,315 (399)

Progress of non‐motor symptoms in early‐onset Parkinson's disease

Ibrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang, Aidi Luo, Shusheng Liao, Mei Liu, Jun Zhang, Zucai Xu   +5 more
wiley   +1 more source

A human skin microbiome reference catalog and the skin microbial landscape of plateau adults

iMetaOmics, EarlyView.
Understanding the skin microbiome is crucial for elucidating its role in health and disease. However, comprehensive studies on the genetic and functional diversity of the skin microbiome in individuals living in extreme environments remain scarce. This work explores the unique characteristics and functional adaptations of the plateau skin microbiome ...
Yi Liu, Zhiming Li, Chao Zhang, Bo Li, Weiwei Jiang, Hang Li, Lei Zhang, Hefu Zhen, Shujun Bao, Xiong Li, Yinuo Liu, Xianzhen Chen, Jinxia Du, Jingjing Xia, Jiucun Wang, Ruijin Guo, Yuzhe Sun, Bo Pan, Wenzhi Lei, Liang Xiao, Jin Zhao, Xin Jin, Wenwei Zhang, Xiaogang Liu, Jian Wang, Min Chen, Wanqing Liao, Wenjie Fang, Chao Nie, Weihua Pan   +29 more
wiley   +1 more source

Prospective association between evening circadian preference and academic functioning in adolescents: the role of daytime sleepiness

Journal of Child Psychology and Psychiatry, Volume 64, Issue 1, Page 175-184, January 2023., 2023
Background There is growing evidence for the role of circadian factors in adolescents' sleep and academic adjustment, with greater evening preference being linked to poorer academic functioning. However, studies have yet to evaluate this association prospectively in adolescence, nor have studies examined daytime sleepiness as a putative mechanism ...
Joseph W. Fredrick, Taryn E. Cook, Joshua M. Langberg, Stephen P. Becker   +3 more
wiley   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Melatonin Is Involved in Regulation of Bermudagrass Growth and Development and Response to Low K+ Stress

Frontiers in Plant Science, 2017
Melatonin (N-acetyl-5-methoxytryptamine) plays critical roles in plant growth and development and during the response to multiple abiotic stresses. However, the roles of melatonin in plant response to K+ deficiency remain largely unknown.
Liang Chen, Jibiao Fan, Zhengrong Hu, Zhengrong Hu, Xuebing Huang, Xuebing Huang, Erick Amombo, Erick Amombo, Ao Liu, Ao Liu, Aoyue Bi, Aoyue Bi, Ke Chen, Yan Xie, Jinmin Fu   +14 more
doaj   +1 more source

Serum metabolic and microbial profiling yields insights into promoting effect of tryptophan‐related metabolites for health longevity in centenarians

iMeta, EarlyView.
Schematic representation of the design. Tryptophan metabolism is enriched in serum metabolites and gut microbiota of centenarians, potentially contributing to healthy longevity. A key tryptophan metabolite 5‐methoxyindoleacetic acid (5‐MIAA) is linked to the Christensenellaceae R‐7 group and exhibits effects of delaying cell senescence, promoting ...
Xiaorou Qiu, Chao Mu, Jie Hu, Jiaxin Yu, Wenbo Tang, Yueli Liu, Yongmei Huang, Yixian Lu, Peihua Tang, Jingzhen Wu, Zixuan Huang, Xianlin Mei, Huaguo Xiang, Hao Lin, Yi Qi, Hui Luo, Xuemeng Li   +16 more
wiley   +1 more source

Role of Medicinal plant‐derived Nutraceuticals as a potential target for the treatment of breast cancer

Journal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
Breast cancer (BC) is one of the most challenging cancers to treat. Nutraceuticals acting by attenuating Hedgehog, NF‐κB, and Wnt/β‐catenin pathways. Nutraceuticals have medical characteristics and may cure cancer Abstract Breast cancer (BC) is one of the most challenging cancers to treat, accounting for many cancer‐related deaths.
Khalid Saad Alharbi, Waleed Hassan Almalki, Hafiz A. Makeen, Mohammed Albratty, Abdulkarim M. Meraya, Rupak Nagraik, Avinash Sharma, Deepak Kumar, Dinesh Kumar Chellappan, Sachin Kumar Singh, Kamal Dua, Gaurav Gupta   +11 more
wiley   +1 more source

Binding and dynamics of melatonin at the interface of phosphatidylcholine-cholesterol membranes.

PLoS ONE, 2019
The characterization of interactions between melatonin, one main ingredient of medicines regulating sleeping rhythms, and basic components of cellular plasma membranes (phospholipids, cholesterol, metal ions and water) is very important to elucidate the ...
Huixia Lu, Jordi Martí
doaj   +1 more source

The role of melatonin in diabetes: therapeutic implications

Archives of Endocrinology and Metabolism, 2015
Melatonin referred as the hormone of darkness is mainly secreted by pineal gland, its levels being elevated during night and low during the day. The effects of melatonin on insulin secretion are mediated through the melatonin receptors (MT1 and MT2).
Shweta Sharma, Hemant Singh, Nabeel Ahmad, Priyanka Mishra, Archana Tiwari   +4 more
doaj   +1 more source

Management of rapid eye movement sleep behavior disorder in patients with Parkinson's disease [PDF]

, 2016
Among all of the devastating effects that Parkinson’s disease (PD) has on an individual, sleep dysfunction is one that can have a profound effect on the entire family of the patient. The most potentially destructive of these sleep syndromes being that of
Jeffries, Michael
core   +1 more source