Results 161 to 170 of about 181,700 (339)

Biosynthesis of melatonin from l-tryptophan by an engineered microbial cell factory

open access: yesBiotechnology for Biofuels and Bioproducts
Background The demand for melatonin is increasing due to its health-promoting bioactivities such as antioxidant and sleep benefits. Although melatonin is present in various organisms, its low content and high extraction cost make it unsustainable ...
Lijuan Wang   +12 more
doaj   +1 more source

Artificial intelligence streamlines scientific discovery of drug–target interactions

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Drug discovery is a complicated process through which new therapeutics are identified to prevent and treat specific diseases. Identification of drug–target interactions (DTIs) stands as a pivotal aspect within the realm of drug discovery and development. The traditional process of drug discovery, especially identification of DTIs, is marked by
Yuxin Yang, Feixiong Cheng
wiley   +1 more source

Effect of Neurotropin on Hyperalgesia Induced by Prostaglandin E2, Naloxone, Melatonin and Dark Condition in Mice

open access: gold, 1987
Hiroshi Takahashi   +4 more
openalex   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

How does melatonin control seasonal reproductive cycles 7 [PDF]

open access: bronze, 1988
Joséphine Arendt   +4 more
openalex   +1 more source

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