Results 41 to 50 of about 227,315 (399)
To what extent does photoperiod affect cattle reproduction? Clinical perspectives of melatonin administration [PDF]
, 2020 The seasonality of reproduction in most mammals is dictated by photoperiod, temperature and nutrition. Melatonin, mainly synthesized in the pineal gland, is generally accepted as the active mediator of photoperiod responses including reproduction.
De Rensis, F. +3 more
core +1 more source
New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation
British Journal of Pharmacology, 2018 In mammals, a central circadian clock, located in the suprachiasmatic nuclei (SCN) of the hypothalamus, tunes the innate circadian physiological rhythms to the ambient 24 h light–dark cycle to invigorate and optimize the internal temporal order.
N. Zisapel
semanticscholar +1 more source
BMC Plant Biology, 2023 Background Melatonin is considered to be a polyfunctional master regulator in animals and higher plants. Exogenous melatonin inhibits plant infection by multiple diseases; however, the role of melatonin in Cucumber green mottle mosaic virus (CGMMV ...
Ling-Ling Yang +10 more
doaj +1 more source
Frontiers in Physiology, 2023 Introduction: Melatonin (5-methoxy-N-acetyl-tryptamine) is a circadian hormone synthesized and secreted by the pineal gland. In addition to regulating circadian rhythms of many physiological functions, melatonin is involved in regulating autonomic ...
Qiyao Yu +9 more
doaj +1 more source
Effects of Duodenal 5-Hydroxytryptophan Perfusion on Melatonin Synthesis in GI Tract of Sheep
Molecules, 2021 The purpose of this study is to investigate the potential effects of 5-hydroxytryptophan (5-HTP) duodenal perfusion on melatonin (MT) synthesis in the gastrointestinal (GI) tract of sheep.
Jun Pan +9 more
doaj +1 more source
Analysis of melatonin content and gene expression in Chinese cherry leaves [PDF]
E3S Web of Conferences, 2020 To investigate the accumulation characteristics and mechanism of melatonin in cherry leaves of different leaf ages, the melatonin content and the expression of synthetic genes in cherry leaves of different leaf ages were measured. The results showed that
Wang Xin +7 more
doaj +1 more source
Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]
, 2015 Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S. +3 more
core +1 more source
Melatonin as a Hormone: New Physiological and Clinical Insights.
Endocrine reviews, 2018 Melatonin is a ubiquitous molecule present in almost every live being from bacteria to humans. In vertebrates, besides being produced in peripheral tissues and acting as an autocrine and paracrine signal, melatonin is centrally synthetized by a ...
J. Cipolla-Neto, F. G. Amaral
semanticscholar +1 more source
Grape Seed Proanthocyanidins Modulate the Hepatic Molecular Clock via MicroRNAs
Molecular Nutrition &Food Research, Volume 66, Issue 23, December 2022., 2022 Jet‐lagged rats and HepG2 cells were used to evaluate if the activity of grape seed proanthocyanidins extract (GSPE) as modulator of hepatic clock genes is mediated by miRNAs. GSPE modulates expression of hepatic Bmal1 and miR‐27b‐3p. Moreover, cosinor‐based analysis reveals that both Bmal1 and miR‐27b‐3p expression follow a circadian rhythm and that ...
Francesca Manocchio +6 more
wiley +1 more source
Melatonin Mitigates Chilling-Induced Oxidative Stress and Photosynthesis Inhibition in Tomato Plants
Antioxidants, 2020 Melatonin has been demonstrated to play a variety of roles in plants. Of particular importance is its role as a potent antioxidative agent. In the present study, we generated melatonin-deficient tomato plants using virus-induced gene silencing (VIGS ...
Meiling Wang, Shuoxin Zhang, Fei Ding
doaj +1 more source