Endogenous circannual rhythm in LH secretion: insight from signal analysis coupled with mathematical modelling [PDF]
In sheep as in many vertebrates, the seasonal pattern of reproduction is timed by the annual photoperiodic cycle, characterized by seasonal changes in the daylength. The photoperiodic information is translated into a circadian profile of melatonin secretion. After multiple neuronal relays (within the hypothalamus), melatonin impacts GnRH (gonadotrophin
arxiv +1 more source
Melatonin for rapid eye movement sleep behavior disorder in Parkinson's disease : a randomised controlled trial [PDF]
Background Melatonin may reduce REM-sleep behavior disorder (RBD) symptoms in Parkinson's disease (PD), though robust clinical trials are lacking. Objective To assess the efficacy of prolonged-release (PR) melatonin for RBD in PD.
Coeytaux Jackson, Alessandra+10 more
core +1 more source
Melatonin metabolism, signaling, and possible roles in plants.
Melatonin is a multifunctional biomolecule found in both animals and plants. In this review, the biosynthesis, levels, signaling, and possible roles of melatonin and its metabolites in plants is summarized. Tryptamine 5-hydroxylase (T5H), which catalyzes
K. Back
semanticscholar +1 more source
Abstract Aim This study examined the mediating effect of circadian rhythm amplitude (LV) and stability (FR) between work stress and sleep quality among Chinese shift‐working nurses (SWNs). Design A cross‐sectional study. Methods Three‐hundred and seventy‐nine nurses working in shifts were investigated by convenient sampling from six hospitals in ...
Songqi Wu+4 more
wiley +1 more source
Salivary melatonin onset in youth at familial risk for bipolar disorder [PDF]
Melatonin secretion and polysomnography (PSG) were compared among a group of healthy adolescents who were at high familial risk for bipolar disorder (HR) and a second group at low familial risk (LR).
Armitage, Roseanne+13 more
core +2 more sources
Abstract Aim It is controversial whether psychotic features are a risk factor for relapse in patients with electroconvulsive therapy‐responsive major depressive disorder. A recent study reported that benzodiazepine receptor agonists reduce relapse of psychotic depression.
Akise Umakoshi+7 more
wiley +1 more source
Melatonin distribution reveals clues to its biological significance in basal metazoans.
Although nearly ubiquitous in nature, the precise biological significance of endogenous melatonin is poorly understood in phylogenetically basal taxa.
Modi Roopin, Oren Levy
doaj +1 more source
"Melatonin": A Case Study on AI-induced Musical Style [PDF]
Although the use of AI tools in music composition and production is steadily increasing, as witnessed by the newly founded AI song contest, analysis of music produced using these tools is still relatively uncommon as a mean to gain insight in the ways AI tools impact music production.
arxiv
Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety [PDF]
<p>Background: Melatonin is extensively used in the USA in a non-regulated manner for sleep disorders. Prolonged release melatonin (PRM) is licensed in Europe and other countries for the short term treatment of primary insomnia in patients aged 55 ...
A Brzezinski+52 more
core +3 more sources
Melatonin: Pharmacology, Functions and Therapeutic Benefits
: Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.), allowing temporal organization of biological functions through circadian rhythms (24-hour cycles) in
S. Tordjman+6 more
semanticscholar +1 more source