Results 51 to 60 of about 242,415 (401)

Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control [PDF]

open access: yes, 2008
The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by decoding changes in nocturnal melatonin secretion.
Alison Downing   +83 more
core   +2 more sources

Melatonin: Pharmacology, Functions and Therapeutic Benefits

open access: yesCurrent Neuropharmacology, 2017
: Background: Melatonin synchronizes central but also peripheral oscillators (fetal adrenal gland, pancreas, liver, kidney, heart, lung, fat, gut, etc.), allowing temporal organization of biological functions through circadian rhythms (24-hour cycles) in
S. Tordjman   +6 more
semanticscholar   +1 more source

Melatonin Mitigates Chilling-Induced Oxidative Stress and Photosynthesis Inhibition in Tomato Plants

open access: yesAntioxidants, 2020
Melatonin has been demonstrated to play a variety of roles in plants. Of particular importance is its role as a potent antioxidative agent. In the present study, we generated melatonin-deficient tomato plants using virus-induced gene silencing (VIGS ...
Meiling Wang, Shuoxin Zhang, Fei Ding
doaj   +1 more source

A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells. [PDF]

open access: yes, 2015
Aging is characterized by a progressive deterioration in physiological functions and metabolic processes. The loss of cells during aging in vital tissues and organs is related to several factors including oxidative stress and inflammation.
Borsani, Elisa   +7 more
core   +1 more source

Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]

open access: yes, 2020
Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core   +1 more source

Melatonin reduces intramuscular fat deposition by promoting lipolysis and increasing mitochondrial function

open access: yesJournal of Lipid Research, 2019
In obesity and diabetes, intramuscular fat (IMF) content correlates markedly with insulin sensitivity, which makes IMF manipulation an area of therapeutic interest.
Kaiqing Liu   +10 more
doaj   +1 more source

Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality?

open access: yesFrontiers in Physiology, 2018
The role of the diet as well as the impact of the dietary habits on human health and disease is well established. Apart from its sleep regulatory effect, the indoleamine melatonin is a well-established antioxidant molecule with multiple health benefits ...
Zukiswa Jiki   +2 more
doaj   +1 more source

Molecular Regulation of Antioxidant Melatonin Biosynthesis by Brassinosteroid Acting as an Endogenous Elicitor of Melatonin Induction in Rice Seedlings

open access: yesAntioxidants, 2022
Gibberellic acid (GA) was recently shown to induce melatonin synthesis in rice. Here, we examined whether brassinosteroids (BRs) also induce melatonin synthesis because BRs and GA show redundancy in many functions. Among several plant hormones, exogenous
Ok Jin Hwang, Kyoungwhan Back
doaj   +1 more source

Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks

open access: yesInternational Journal of Molecular Sciences, 2019
Aging and various age-related diseases are associated with reductions in melatonin secretion, proinflammatory changes in the immune system, a deteriorating circadian system, and reductions in sirtuin-1 (SIRT1) activity.
R. Hardeland
semanticscholar   +1 more source

Importance of Melatonin in Assisted Reproductive Technology and Ovarian Aging

open access: yesInternational Journal of Molecular Sciences, 2020
Melatonin is probably produced in all cells but is only secreted by the pineal gland. The pineal secretion of melatonin is determined by the light–dark cycle, and it is only released at night.
H. Tamura   +12 more
semanticscholar   +1 more source

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