Results 81 to 90 of about 227,315 (399)
Melatonin and inflammation—Story of a double‐edged blade
Journal of Pineal Research, 2018 Melatonin is an immune modulator that displays both pro‐ and anti‐inflammatory properties. Proinflammatory actions, which are well documented by many studies in isolated cells or leukocyte‐derived cell lines, can be assumed to enhance the resistance ...
R. Hardeland
semanticscholar +1 more source
Importance of Melatonin in Assisted Reproductive Technology and Ovarian Aging
International Journal of Molecular Sciences, 2020 Melatonin is probably produced in all cells but is only secreted by the pineal gland. The pineal secretion of melatonin is determined by the light–dark cycle, and it is only released at night.
H. Tamura +12 more
semanticscholar +1 more source
A comparison of melatonin and α-lipoic acid in the induction of antioxidant defences in L6 rat skeletal muscle cells. [PDF]
, 2015 Aging is characterized by a progressive deterioration in physiological functions and metabolic processes. The loss of cells during aging in vital tissues and organs is related to several factors including oxidative stress and inflammation.
Borsani, Elisa +7 more
core +1 more source
Frontiers in Plant Science, 2019 The protective role of melatonin in plants against various abiotic stresses have been widely demonstrated, but poorly explored in organ-specific responses and the transmission of melatonin signals across organs.
Bo Huang +9 more
semanticscholar +1 more source
Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles
Advanced Science, EarlyView.Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang +4 more
wiley +1 more source
Supersulfide biology and translational medicine for disease control
British Journal of Pharmacology, EarlyView., 2023 Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu +5 more
wiley +1 more source
Journal of Integrative Agriculture, 2021 Anthocyanins are important components in the peel of red pears and contribute to the appearance of the fruit. Melatonin application is known to affect anthocyanin biosynthesis, but the effect of preharvest melatonin application on fruit coloration ...
Hui-li SUN +5 more
doaj
Biology, 2019 Melatonin is well known to modulate the sleep−wake cycle. Accumulating evidence suggests that melatonin also has favorable effects such as anti-oxidant and anti-inflammatory properties in numerous disease models. It has been reported that melatonin
Jong Woo Kim +5 more
doaj +1 more source
Journal of Sleep Research, 1996 The hypnotic action of melatonin 5 mg p.o. was explored in 15 subjects with psychophysiological insomnia in a double‐blind controlled self‐report questionnaire study. Melatonin or placebo was taken at 20.00 hours for a 1‐week period in random order.
Gilbert Lemmens, C M Ellis, J D Parkes
openaire +2 more sources
Phototherapy via Modulation of β‐Amyloid in Combating Alzheimer's Disease
Aggregate, EarlyView.This review introduces the light‐regulated Aβ aggregation, highlighting four applications: photodynamic therapy (PDT), photothermal therapy (PTT), photopharmacology, and photobiomodulation (PBM) systems. It also summarizes the current issues and proposes the prospects of photo‐induced modulation of Aβ aggregation and clearance as a therapeutic strategy
Yunhua Zhang +4 more
wiley +1 more source