Methicillin-resistant Staphylococcus epidermidis (MRSE) strains are increasingly emerging as serious pathogens because they can be resistant to many antibiotics called multidrug resistance (MDR) that limit the therapeutic options.
Rasoul Mirzaei +11 more
doaj +1 more source
Asian honeybee venom is widely used in traditional oriental medicine. Melittin is the main component of Asian honeybee venom. In the present study, an ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QqTOF-MS ...
Sheng Huang +4 more
doaj +1 more source
Characterizing Single Polymeric and Protein Nanoparticles with Surface Plasmon Resonance Imaging Measurements [PDF]
Near-infrared surface plasmon resonance imaging (SPRI) microscopy is used to detect and characterize the adsorption of single polymeric and protein nanoparticles (PPNPs) onto chemically modified gold thin films in real time.
Corn, Robert M. +3 more
core +2 more sources
Micro/nanorobots for detecting and eliminating biological and chemical warfare agents
Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li +4 more
wiley +1 more source
Export of honeybee prepromelittin in Escherichia coli depends on the membrane potential but does not depend on proteins secA and secY [PDF]
Honeybee prepromelittin (70 amino acid residues), the precursor of an eukaryotic secretory protein, and a hybrid protein between prepromelittin and mouse dihydrofolate reductase (257 amino acid residues) were expressed in Escherichia coli and ...
Cobet, Werner W. E. +3 more
core
Metabolomic profiling of the synergistic effects of melittin in combination with cisplatin on ovarian cancer cells [PDF]
Melittin, the main peptide present in bee venom, has been proposed as having potential for anticancer therapy; the addition of melittin to cisplatin, a first line treatment for ovarian cancer, may increase the therapeutic response in cancer treatment via
Alonezi, Sanad +10 more
core +1 more source
Bottom‐up Strategies for Generating Polymer Protocells That Mimic Cellular Communication
This review focuses on polymeric protocells produced using a bottom‐up approach. Polymer‐based assemblies guarantee stability and designability by adjusting the properties of the amphiphilic copolymers used. The review covers protocell architectures, production, and their intra‐ and intercellular communication mechanisms.
Gloria Saorin +3 more
wiley +1 more source
Effect of Melittin on Metabolomic Profile and Cytokine Production in PMA-Differentiated THP-1 Cells
Melittin, the major active peptide of honeybee venom (BV), has potential for use in adjuvant immunotherapy. The immune system response to different stimuli depends on the secretion of different metabolites from macrophages.
Abdulmalik M. Alqarni +4 more
doaj +1 more source
Antimicrobial Cyclic Peptidomimetics
Singular macromolecular cationic, amphipathic cyclic peptidomimetics with poly(2‐oxazoline)s‐esque backbone structure that undergo self‐assembly in water to form uniform nanoparticles were developed. The cyclic peptidomimetics, which act on bacterial cell membranes, exhibit hydrophobic‐dependent antimicrobial activity and toxicity.
Hao Luo, Edgar H. H. Wong
wiley +1 more source
Ultrastructural observation on sterilization of melittin [PDF]
ABSTACT: The effects of melittin on growth and bacteriostasis of four pathogens were extensively investigated using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The results indicated that the melittin had a marked bacteriostatic effect on the four pathogenic bacteria. Among these, E.
Wang, GuanLin +4 more
openaire +2 more sources

