Results 81 to 90 of about 15,825 (230)

Effect of melittin on mice stomach

Saudi Journal of Biological Sciences, 2014
Melittin, the main bee venom component, has many positive biological effects and a relatively low toxicity in various cell types. However, there is no evidence of the effect of melittin on gastrointestinal cells. In the present study, we investigated the histological and immuonohistochemical effects of melittin on mice stomach.
Abu-Zinadah, Osama, Rahmy, Tarek, Alahmari, Abeer, Abdu, Faiza   +3 more
openaire   +2 more sources

Health Effects of Bee Products: A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Nutritional composition of bee products and some health effects. ABSTRACT Honey, bee pollen, propolis, bee bread, royal jelly, bee venom, beeswax, and apilarnil are among the bee‐derived products that may serve health‐related purposes, as they exhibit various biological activities such as antibacterial, antiviral, antifungal, antioxidant, anti ...
Nevin Sanlier, Elif Yildiz Kaya, Ikbal Irem Yucel   +2 more
wiley   +1 more source

Isolating Melittin from Bee Venom and Evaluating its Effect on Proliferation of Gastric Cancer Cells

Basic & Clinical Cancer Research, 2013
Background : Gastric cancer (GC) is one of the most common cancers worldwide and in Iran. As conventional therapies such as surgery and chemotherapy are invasive with adverse effects, current studies are important as they are conducted to find natural ...
Amir Mahmoodzadeh, Ali Morady, Hannaneh Zarrinnahad, Kamran Pooshang Bagheri, Pooria Ghasemi-Dehkordi, Mahdi Mahdavi, Delavar Shahbazzadeh, Hamidreza Shahmorady   +7 more
doaj  

Novel Molecules for Intra-Oral Delivery of Antimicrobials to Prevent and Treat Oral Infectious Diseases [PDF]

, 2008
New molecules were designed for efficient intra-oral delivery of antimicrobials to prevent and treat oral infection. The salivary statherin fragment, which has high affinity for the tooth enamel, was used as a carrier peptide. This was linked through the
Dentino, Andrew R., Raj, Periathamby A., Rajkumar, Latha   +2 more
core   +1 more source

Hydrogels for Cancer Immunotherapy: Strategies From Construction to Application

MedComm, Volume 7, Issue 2, February 2026.
Hydrogels offer an innovative platform for cancer immunotherapy. Through tailorable crosslinking strategies, they form customizable drug delivery platforms that address diverse therapeutic requirements by loading specific immunotherapeutic agents. These systems demonstrate significant clinical potential for precise tumor immunotherapy.
Xiaohua Chen, Shan Wu, Yueyang Zhang, Lilu Feng, Yang Chen, Xuzhao Yang, Ke Men, Jiuqun Zhu, Ming Li   +8 more
wiley   +1 more source

Precision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles [PDF]

, 2019
Over 95% of pancreatic adenocarcinomas (PDACs), as well as a large fraction of other tumor types, such as colorectal adenocarcinoma, are driven by KRAS activation. However, no direct RAS inhibitors exist for cancer therapy.
Bi, Ye, Brooks, Candace, DeNardo, David G, Fields, Ryan C, Fleming, Timothy, Gillanders, William E, Goedegebuure, S Peter, Hawkins, William G, Krasnick, Bradley A, Pan, Hua, Sankpal, Narendra, Strand, Matthew S, Wetzel, Christopher, Wickline, Samuel A, Zhang, Xiuli   +14 more
core   +1 more source

Antiviral activity of animal venom peptides and related compounds [PDF]

, 2017
Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense.
Mata, Élida Cleyse Gomes da Mata, Mourão, Caroline Barbosa Farias, Rangel, Marisa, Schwartz, Elisabeth Nogueira Ferroni   +3 more
core   +2 more sources

Zweikanal‐Fluoreszenz‐Assays mit supramolekularen Wirt/Farbstoff‐Reporterpaaren zur Kartierung der Membranaktivität von Peptiden

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Membranaktive Peptide (MAPs) wie zellpenetrierende Peptide (CPPs) und antimikrobielle Peptide (AMPs) können Lipidmembranen durchdringen und Membranporen bilden. Die Kombination aus einem Farbstoff‐Efflux‐Assay und einem supramolekularen Tandem‐Membran‐Assay in einem Zweikanalformat ermöglicht eine fortgeschrittene mechanistische Charakterisierung und ...
Mohammad A. Alnajjar, Sandra N. Schöpper, Malavika Pramod, Thomas Reingolz, Lina Müller, Justin Neumann, Mohamed Nilam, Werner M. Nau, Andreas Hennig   +8 more
wiley   +1 more source

The role of hydrophobic amino acid grafts in the enhancement of membrane-disruptive activity of pH-responsive pseudo-peptides [PDF]

, 2009
pH-responsive polymers have been synthesised by grafting l-valine (PV-75), l-leucine (PL-75) and l-phenylalanine (PP-75) onto the pendant carboxylic acid moieties of a pseudo-peptide, poly(l-lysine iso-phthalamide), at a stoichiometric degree of ...
Chen, R, Eccleston, ME, Khormaee, S, Slater, NKH   +3 more
core   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source