Results 51 to 60 of about 17,959 (132)
Long-Term NMDAR Antagonism Correlates Weight Loss With Less Eating
Frontiers in Psychiatry, 2019 Memantine hydrochloride is an uncompetitive N-methyl-D-aspartate (NMDA) antagonist for treatment of moderate-to-severe Alzheimer's disease. Several studies have shown that memantine can significantly correct the binge-like eating behavior in human and ...
Shi-Ning Deng +7 more
doaj +1 more source
Exploration of Neuroprotective Therapy, 2023 Aim: To compare the efficacy of memantine with that of valproate as a prophylactic treatment for episodic migraine within three months. The efficacy, safety, and response rate were evaluated.
Damaris Vazquez-Guevara +5 more
doaj +1 more source
Suzetrigine as a novel treatment for headache disorders: A case series
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Suzetrigine is a selective voltage‐gated sodium channel blocker that was recently approved by the US Food and Drug Administration for the treatment of acute pain. We retrospectively evaluated the efficacy and tolerability of suzetrigine for the treatment of different headache disorders in patients refractory to standard treatments in an ...
Molly Fensterwald +15 more
wiley +1 more source
Bioequivalence study drug containing memantine
Фармакокинетика и Фармакодинамика, 2013 At present, Russia has developed domestic analogue of Memantine Akatinol — Memaneyrin in the form of droplets which is pharmaceutically equivalent drug memantine Akatinol.
A. A. Karlitskaya +5 more
doaj
Comprehensive Psychiatry, 2020 Background: Major depressive disorder (MDD) is frequently associated with cognitive deficits and high copper levels. Dysfunction of N-methyl-d-aspartate (NMDA) receptors has been postulated to underlie MDD pathogenesis.
Zhinan Li +13 more
doaj +1 more source
Psychiatry and Clinical Neurosciences, EarlyView.Aim To determine the smallest worthwhile difference (SWD) for lecanemab, a disease‐modifying drug for Alzheimer's disease (AD), among the general Japanese population using a benefit‐harm trade‐off method. Methods We conducted an online survey with 658 participants to evaluate their preferences for the treatment effect of lecanemab, given its associated
Aran Tajika +5 more
wiley +1 more source
Effect of Memantine on Overactive Detrusor in Rats With Spinal Cord Injury
Kaohsiung Journal of Medical Sciences, 2010 The aim of this study was to determine the effect of memantine on overactive detrusor (OAD) 15 days after spinal cord injury (SCI) in rats. Twenty-eight adult Wistar rats were used in this study.
Cüneyd Özkürkçügil +2 more
doaj +1 more source
Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.Abstract INTRODUCTION Obstructive sleep apnea (OSA) is a potential risk factor for cognitive impairment and dementia; however, its contribution in midlife and interactions with APOE ε4 remain unclear. METHODS Participants were 2795 cognitively unimpaired, middle‐aged adults enrolled in the Healthy Brain Project. OSA status was determined by self‐report.
Gabriel T. Abdelmessih +4 more
wiley +1 more source
Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Emerging Medications in Facial Nerve Recovery: A Systematic Review and Meta‐Analysis
OTO Open, Volume 10, Issue 3, July-September 2026.Abstract Objective To systematically review the literature for medical therapies that promote facial nerve regeneration and recovery. Data Sources PubMed/Medline, Embase, and SCOPUS databases were searched for English‐language studies published from inception through May 2025.
Kimberly Chan +5 more
wiley +1 more source