Results 61 to 70 of about 24,117 (172)

Effect of Memantine on Overactive Detrusor in Rats With Spinal Cord Injury

Kaohsiung Journal of Medical Sciences, 2010
The aim of this study was to determine the effect of memantine on overactive detrusor (OAD) 15 days after spinal cord injury (SCI) in rats. Twenty-eight adult Wistar rats were used in this study.
Cüneyd Özkürkçügil, Osman Kömür, Levend Özkan   +2 more
doaj   +1 more source

Alleviation of cognitive deficits and high copper levels by an NMDA receptor antagonist in a rat depression model

Comprehensive Psychiatry, 2020
Background: Major depressive disorder (MDD) is frequently associated with cognitive deficits and high copper levels. Dysfunction of N-methyl-d-aspartate (NMDA) receptors has been postulated to underlie MDD pathogenesis.
Zhinan Li, Guodong Wang, Shuming Zhong, Xiaoxiao Liao, Shunkai Lai, Yanyan Shan, Junhao Chen, Lu Zhang, Qianyi Lu, Shiyi Shen, Hui Huang, Yiliang Zhang, Li Zhang, Yanbin Jia   +13 more
doaj   +1 more source

Memantine effects on auditory discrimination and training in schizophrenia patients [PDF]

, 2020
The uncompetitive low-affinity NMDA receptor antagonist, memantine, acutely increases electrophysiological measures of auditory information processing in both healthy subjects (HS) and patients with schizophrenia. Memantine effects on functional measures
Bhakta, Savita G, Clifford, Royce Ellen, Thomas, Michael L, Joshi, Yash B, Kotz, Juliana, Swerdlow, Neal R, Talledo, Jo, Light, Gregory A, Molina, Juan L, Roberts, Benjamin Z, Royce Ellen Clifford, Juliana Kotz, Jo Talledo, Juan L. Molina, Benjamin Z. Roberts, Michael L. Thomas, Gregory A. Light, Yash B. Joshi, Neal R. Swerdlow, Savita G. Bhakta   +19 more
core   +1 more source

Hip Fracture Risk of Lemborexant and Suvorexant in Comparison With Z‐Drugs: A Target Trial Emulation

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Lemborexant and suvorexant are widely used dual orexin receptor antagonists (DORAs) for the pharmacological treatment of insomnia. Although they are generally considered safer than benzodiazepine receptor agonists (Z‐drugs) regarding adverse events including hip fractures, evidence from direct comparisons remains limited. This study
Yuichiro Matsuo, Hayato Yamana, Yusuke Sasabuchi, Hiroki Matsui, Takahide Kohro, Hideo Yasunaga   +5 more
wiley   +1 more source

Effect of memantine on cognition.

, 2016
Effect of memantine on cognition.
Xavier Durando (2600911), Christine Villatte (2600917), Laurence Daulhac (441656), Delphine Roux (2600902), Bruno Pereira (415597), Véronique Morel (2600908), Dominique Joly (12402), Gisèle Pickering (2600914), Claude Dubray (195841), Catherine Coudert (2600905)   +9 more
core   +1 more source

Clinical practices in the management of cervical Hansen type I intervertebral disc herniation among veterinary neurologists in North America and Europe

Journal of Small Animal Practice, EarlyView.
Objectives To describe current clinical practices in the management of cervical Hansen type I intervertebral disc herniation among American College of Veterinary Internal Medicine/European College of Veterinary Neurology neurologists. Materials and Methods An anonymous web‐based survey was distributed via professional listservs between October and ...
A. Mondino, M. Riobó, N. J. Olby, S. Moore, P. J. Early   +4 more
wiley   +1 more source

N‐methyl‐D‐aspartate receptor antagonists for controlling pain in dogs

Journal of Small Animal Practice, EarlyView.
This is a mini review published by the World Small Animal Veterinary Association's Pain Committee. This article provides an assessment of the scientific evidence of N‐methyl‐d‐aspartate receptor antagonists for controlling pain in dogs while identifying current knowledge gaps.
P. W. Kronen, B. D. X. Lascelles, B. P. Monteiro, J. C. Murrell, S. A. Robertson, P. V. Steagall, B. Wright   +6 more
wiley   +1 more source

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology
Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
doaj   +1 more source

The NMDA antagonist memantine affects training induced motor cortex plasticity – a study using transcranial magnetic stimulation [ISRCTN65784760]

BMC Neuroscience, 2005
Background Training of a repetitive synchronised movement of two limb muscles leads to short-term plastic changes in the primary motor cortex, which can be assessed by transcranial magnetic stimulation (TMS) mapping.
Schwenkreis Peter, Witscher Katja, Pleger Burkhard, Malin Jean-Pierre, Tegenthoff Martin   +4 more
doaj   +1 more source

Acute Pharmacokinetics of Memantine in the Mouse

, 2011
The pharmacokinetics of memantine, a widely prescribed medication in the United States and the European Union for the treatment of moderate-to-severe Alzheimer’s disease (AD), have not been well explored in the mouse.
Bechara J. Saab, John C. Roder
core   +1 more source