Results 81 to 90 of about 712,406 (355)

Intoxication of host cells by the T3SS phospholipase ExoU: PI(4,5)P2-associated, cytoskeletal collapse and late phase membrane blebbing. [PDF]

PLoS ONE, 2014
Pseudomonas aeruginosa is an opportunistic pathogen that is associated with hospital-acquired infections, ventilator-associated pneumonia, and morbidity of immunocompromised individuals. A subpopulation of P.
Hiromi Sato, Dara W Frank
doaj   +1 more source

Redox linked flavin sites in extracellular decaheme proteins involved in microbe-mineral electron transfer [PDF]

, 2015
Extracellular microbe-mineral electron transfer is a major driving force for the oxidation of organic carbon in many subsurface environments. Extracellular multi-heme cytochromes of the Shewenella genus play a major role in this process but the mechanism
A Okamoto, AC Mitchell, AGW Leslie, AM Waterhouse, AS Beliaev, CL Reardon, D Coursolle, D Ghosal, DE Ross, DJ Richardson, DJ Richardson, DJ Richardson, DK Thompson, E Marsili, ED Brutinel, F Sievers, GF White, GM Boratyn, GN Murshudov, I Letunic, JK Fredrickson, L Shi, L Shi, MJ Daly, MJ Daly, MJ Edwards, MJ Edwards, MJ Edwards, MY El-Naggar, P Taylor, PD Adams, RJ Morris, RS Hartshorne, S Bailey, S Pirbadian, TA Clarke   +35 more
core   +1 more source

CD46 Is a Protein Receptor for Human Adenovirus Type 64

Viruses
Certain species D human adenoviruses (HAdV-D19, -D37, and -D64) are causative agents of epidemic keratoconjunctivitis. HAdV-D37 has previously been shown to bind CD46 (membrane cofactor protein) and sialic acid as adhesion receptors.
Eugene Y. Wu, Alexander M. Robertson, Hanglin (Henry) Zhu, Corina Stasiak, Laura A. Murray-Nerger, Emily Romanoff, Jesse Woon, Beth A. Bromme, Jason G. Smith   +8 more
doaj   +1 more source

The Host Cell Receptors for Measles Virus and Their Interaction with the Viral Hemagglutinin (H) Protein

Viruses, 2016
The hemagglutinin (H) protein of measles virus (MeV) interacts with a cellular receptor which constitutes the initial stage of infection. Binding of H to this host cell receptor subsequently triggers the F protein to activate fusion between virus and ...
Liang-Tzung Lin, Christopher D. Richardson   +1 more
doaj   +1 more source

Bacterial TANGO2 homologs are heme-trafficking proteins that facilitate biosynthesis of cytochromes c

mBio, 2023
Heme, an essential molecule for virtually all living organisms, acts primarily as a cofactor in a large number of proteins. However, how heme is mobilized from the site of synthesis to the locations where hemoproteins are assembled remains largely ...
Sirui Han, Kailun Guo, Wei Wang, Yizhi J. Tao, Haichun Gao   +4 more
doaj   +1 more source

The Distal Short Consensus Repeats 1 and 2 of the Membrane Cofactor Protein CD46 and Their Distance from the Cell Membrane Determine Productive Entry of Species B Adenovirus Serotype 35

Journal of Virology, 2005
Christoph Fleischli, Sandra Verhaagh, Menzo Havenga, Dominique Sirena, Walter Schaffner, Roberto Cattaneo, Urs F. Greber, Silvio Hemmi   +7 more
openalex   +2 more sources

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Long‐term efficacy of encapsulated xenogeneic islet transplantation: Impact of encapsulation techniques and donor genetic traits

Journal of Diabetes Investigation
Aims/Introduction To investigate the long‐term efficacy of various encapsulated xenogeneic islet transplantation, and to explore the impact of different donor porcine genetic traits on islet transplantation outcomes.
Heon‐Seok Park, Eun Young Lee, Young‐Hye You, Marie Rhee, Jong‐Min Kim, Seong‐Soo Hwang, Poong‐Yeon Lee   +6 more
doaj   +1 more source

Rab11-FIP1C and Rab14 direct plasma membrane sorting and particle incorporation of the HIV-1 envelope glycoprotein complex. [PDF]

PLoS Pathogens, 2013
The incorporation of the envelope glycoprotein complex (Env) onto the developing particle is a crucial step in the HIV-1 lifecycle. The long cytoplasmic tail (CT) of Env is required for the incorporation of Env onto HIV particles in T cells and ...
Mingli Qi, Janice A Williams, Hin Chu, Xuemin Chen, Jaang-Jiun Wang, Lingmei Ding, Ehiole Akhirome, Xiaoyun Wen, Lynne A Lapierre, James R Goldenring, Paul Spearman   +10 more
doaj   +1 more source