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Coming together to define membrane contact sites [PDF]
Nature Communications, 2019 Given the recent growing interest in interorganelle membrane contact sites, the field will benefit from clear rules to define and study them. In this Perspective, a panel of experts aims to provide this growing field with guidelines for experimental ...
Luca Scorrano +14 more
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Membrane Contact Sites in Autophagy [PDF]
Cells, 2022 Eukaryotes utilize different communication strategies to coordinate processes between different cellular compartments either indirectly, through vesicular transport, or directly, via membrane contact sites (MCSs).
Emma Zwilling, Fulvio Reggiori
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How Membrane Contact Sites Shape the Phagophore [PDF]
Contact, 2023 During macroautophagy, phagophores establish multiple membrane contact sites (MCSs) with other organelles that are pivotal for proper phagophore assembly and growth. In S.
Cristina Capitanio +2 more
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Intracellular Membrane Contact Sites in Skeletal Muscle Cells [PDF]
MembranesIntracellular organelles are common to eukaryotic cells and provide physical support for the assembly of specialized compartments. In skeletal muscle fibers, the largest intracellular organelle is the sarcoplasmic reticulum, a specialized form of the ...
Matteo Serano +5 more
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Channels, Transporters, and Receptors at Membrane Contact Sites [PDF]
ContactMembrane contact sites (MCSs) are specialized regions where two or more organelle membranes come into close apposition, typically separated by only 10–30 nm, while remaining distinct and unfused.
Maria Casas, Eamonn James Dickson
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Interorganellar Communication Through Membrane Contact Sites in [PDF]
Contact, 2023 Apicomplexan parasites are a group of protists that cause disease in humans and include pathogens like Plasmodium spp ., the causative agent of malaria, and Toxoplasma gondii , the etiological agent of toxoplasmosis and one of the most ubiquitous human ...
Diego Huet Dr, Silvia N. J. Moreno Dr
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Membrane Contact Sites in Proteostasis and ER Stress Response [PDF]
ContactExecution of all cellular functions depends on a healthy proteome, whose maintenance requires multimodal oversight. Roughly a third of human proteins reside in membranes and thus present unique topological challenges with respect to biogenesis and ...
Febe Vermue +2 more
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Organelles are miscommunicating: Membrane contact sites getting hijacked by pathogens [PDF]
Virulence, 2023 Membrane Contact Sites (MCS) are areas of close apposition of organelles that serve as hotspots for crosstalk and direct transport of lipids, proteins and metabolites.
Pratyashaa Paul, Bhavana Tiwari
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Remodeling of ER Membrane Contact Sites During Cell Division [PDF]
ContactMembrane contact sites (MCS) provide specialized conduits for inter-organelle communications to maintain cellular homeostasis. Most organelles are interconnected, which supports their coordination and function.
Fang Yu, Khaled Machaca
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C: Cryo-Electron Microscopy of Membrane Contact Sites and Their Components [PDF]
ContactElectron microscopy has played a pivotal role in elucidating the ultrastructure of membrane contact sites between cellular organelles. The advent of cryo-electron microscopy has ushered in the ability to determine atomic models of constituent proteins or
Cyan Ching +4 more
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