Results 31 to 40 of about 666,510 (287)

ER-Mitochondria contact sites : a new regulator of cellular calcium flux comes into play [PDF]

, 2016
Endoplasmic reticulum (ER)-mitochondria membrane contacts are hotspots for calcium signaling. In this issue, Raturi et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201512077) show that the thioredoxin TMX1 inhibits the calcium pump SERCA2b at ...
Anelli, Appenzeller-Herzog, Bittremieux, Booth, Csordás, Cárdenas, Cárdenas, Doghman-Bouguerra, Geert Bultynck, Hayashi, Higo, Krols, Li, Lynes, Lynes, Marchi, Marino, Michiel Krols, Raturi, Rizzuto, Roderick, Sophie Janssens, Szabadkai   +22 more
core   +2 more sources

Mitochondrial protein import [PDF]

, 1989
Proteolytic degradation of receptor sites on the mitochondrial surface strongly reduces the efficiency of mitochondrial protein import. The remaining residual import still involves basic mechanisms of protein import, including: insertion of precursors ...
Neupert, Walter, Pfaller, Rupert, Pfanner, Nikolaus   +2 more
core   +4 more sources

Interactome Analysis of the ER Stress Sensor Perk Uncovers Key Components of ER-Mitochondria Contact Sites and Ca Signalling

Contact, 2021
We recently reported that the ER stress kinase PERK regulates ER-mitochondria appositions and ER– plasma membrane (ER-PM) contact sites, independent of its canonical role in the unfolded protein response. PERK regulation of ER-PM contacts was revealed by
Maria Livia Sassano, Rita Derua, Etienne Waelkens, Patrizia Agostinis, Alexander R van Vliet   +4 more
doaj   +1 more source

Lipid transfer proteins do their thing anchored at membrane contact sites… but what is their thing? [PDF]

, 2016
Membrane contact sites are structures where two organelles come close together to regulate flow of material and information between them. One type of inter-organelle communication is lipid exchange, which must occur for membrane maintenance and in ...
Levine, TP, Wong, LH
core   +1 more source

Transport of proteins into mitochondria [PDF]

, 1985
Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Neupert, Walter, Schleyer, Manfred
core   +1 more source

Membrane Contact Sites and Organelles Interaction in Plant Autophagy

Frontiers in Plant Science, 2020
Autophagy is an intracellular trafficking and degradation system for recycling of damaged organelles, mis-folded proteins and cytoplasmic constituents. Autophagy can be divided into non-selective autophagy and selective autophagy according to the cargo ...
Hao Ye, Changyang Ji, Rongfang Guo, Rongfang Guo, Liwen Jiang, Liwen Jiang   +5 more
doaj   +1 more source

Pex30-dependent membrane contact sites maintain ER lipid homeostasis. [PDF]

J Cell Biol
AbstractIn eukaryotic cells, communication between organelles and the coordination of their activities depend on membrane contact sites (MCS). How MCS are regulated under the dynamic cellular environment remains poorly understood. Here, we investigate how Pex30, a membrane protein localized to the endoplasmic reticulum (ER), regulates multiple MCS in ...
Ferreira JV, Ahmed Y, Heunis T, Jain A, Johnson E, Räschle M, Ernst R, Vanni S, Carvalho P.   +8 more
europepmc   +4 more sources

Editorial: Membrane lipids in T cell functions [PDF]

, 2018
Plasma membrane lipids play essential roles in regulating T cell signaling, differentiation, and effector functions. The major lipid species in the plasma membrane are glycerophospholipids, sphingolipids, and sterol lipids.
Tuosto, Loretta, Xu, Chenqi
core   +1 more source

E-Syt1 Regulates Neuronal Activity-Dependent Endoplasmic Reticulum–Plasma Membrane Junctions and Surface Expression of AMPA Receptors

Contact, 2023
Endoplasmic reticulum (ER)–plasma membrane (PM) contact sites/junctions play important roles in cell physiology including signal transduction, ion and lipid transfer, and membrane dynamics.
Ranran Mao, Chunfang Tong, Jia-Jia Liu
doaj   +1 more source

Biogenesis of the mitochondrial phosphate carrier [PDF]

, 1991
The mitochondrial phosphate carrier (PiC) is a member of the family of inner-membrane carrier proteins which are generally synthesized without a cleavable presequence.
Adrian G. S., Aquila H., Aquila H., Arends H., Chen W.-J., Cheng M. K., Daum G., Eilers M., Ferreira G. C., Freeman K. B., Goglia F., Kolbe H. V. J., Kramer R., Liu X., Melton D. A., Murakami K., Nicholson D. W., Pelham H. R. B., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Pfanner N., Phelps A., Ricquier D., Ridley R. G., Runswick M. J., Runswick M. J., Schleyer M., Schleyer M., Schleyer M., Schwaiger M., Smagula C. S., Wachter E., Zimmermann R.   +36 more
core   +1 more source