Animal Cell Cytokinesis: The Rho-Dependent Actomyosin-Anilloseptin Contractile Ring as a Membrane Microdomain Gathering, Compressing, and Sorting Machine [PDF]
Frontiers in Cell and Developmental Biology, 2020 Cytokinesis is the last step of cell division that partitions the cellular organelles and cytoplasm of one cell into two. In animal cells, cytokinesis requires Rho-GTPase-dependent assembly of F-actin and myosin II (actomyosin) to form an equatorial ...
Sabrya C. Carim +3 more
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The cytosolic N-terminus of CD317/tetherin is a membrane microdomain exclusion motif [PDF]
Biology Open, 2013 Summary The integral membrane protein CD317/tetherin has been associated with a plethora of biological processes, including restriction of enveloped virus release, regulation of B cell growth, and organisation of membrane microdomains.
Peter G. Billcliff +3 more
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Membrane Microdomain Disassembly Inhibits MRSA Antibiotic Resistance. [PDF]
Cell, 2017 Summary A number of bacterial cell processes are confined functional membrane microdomains (FMMs), structurally and functionally similar to lipid rafts of eukaryotic cells.
García-Fernández E +10 more
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Escherichia coli SPFH Membrane Microdomain Proteins HflKC Contribute to Aminoglycoside and Oxidative Stress Tolerance. [PDF]
Microbiol Spectr, 2023 Eukaryotic cells often segregate physiological processes in cholesterol-rich functional membrane microdomains. These domains are also called lipid rafts and contain proteins of the stomatin, prohibitin, flotillin, and HflK/C (SPFH) superfamily, which are
Wessel AK +10 more
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Cryo-EM architecture of a near-native stretch-sensitive membrane microdomain. [PDF]
NatureBiological membranes are partitioned into functional zones termed membrane microdomains, which contain specific lipids and proteins1–3. The composition and organization of membrane microdomains remain controversial because few techniques are available ...
Kefauver JM +14 more
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RaftProt V2: understanding membrane microdomain function through lipid raft proteomes. [PDF]
Nucleic Acids Res, 2019 Cellular membranes feature dynamic submicrometer-scale lateral membrane domainsvariously referred to as lipid rafts, membrane rafts or glycosphingolipid-enriched microdomains (GEM).
Mohamed A, Shah AD, Chen D, Hill MM.
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Feeding-fasting dependent recruitment of membrane microdomain proteins to lipid droplets purified from the liver. [PDF]
PLoS One, 2017 Lipid droplets (LDs) are cellular stores of neutral fat that facilitate lipid and protein trafficking in response to metabolic cues. Unlike other vesicles, the phospholipid membrane on the LD is a monolayer.
Sadh K, Rai P, Mallik R.
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A plasma membrane microdomain compartmentalizes ephrin-generated cAMP signals to prune developing retinal axon arbors. [PDF]
Nat Commun, 2016 The development of neuronal circuits is controlled by guidance molecules that are hypothesized to interact with the cholesterol-enriched domains of the plasma membrane termed lipid rafts.
Averaimo S +7 more
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CLN3 loss disturbs membrane microdomain properties and protein transport in brain endothelial cells. [PDF]
J Neurosci, 2013 Juvenile neuronal ceroid lipofuscinosis (JNCL) is a fatal childhood-onset neurodegenerative disorder caused by mutations in ceroid lipofuscinosis neuronal-3 (CLN3), a hydrophobic transmembrane protein of unresolved function.
Tecedor L +5 more
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Structural insights into the membrane microdomain organization by SPFH family proteins. [PDF]
Cell Res, 2022 Ma C +6 more
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