The membrane-associated form of α(s1)-casein interacts with cholesterol-rich detergent-resistant microdomains. [PDF]
Caseins, the main milk proteins, interact with colloidal calcium phosphate to form the casein micelle. The mesostructure of this supramolecular assembly markedly influences its nutritional and technological functionalities.
Annabelle Le Parc +5 more
doaj +1 more source
Shining light on the function of NPH3/RPT2-like proteins in phototropin signalling [PDF]
No abstract ...
Christie, John M. +3 more
core +1 more source
Chitin perception in plasmodesmata characterizes submembrane immune-signaling specificity in plants [PDF]
The plasma membrane (PM) is composed of heterogeneous subdomains, characterized by differences in protein and lipid composition. PM receptors can be dynamically sorted into membrane domains to underpin signaling in response to extracellular stimuli.
Bellandi, Annalisa +9 more
core +2 more sources
Variational Methods for Biomolecular Modeling
Structure, function and dynamics of many biomolecular systems can be characterized by the energetic variational principle and the corresponding systems of partial differential equations (PDEs).
A Ivankin +114 more
core +1 more source
Domain Growth Kinetics in a Cell-sized Liposome [PDF]
We investigated the kinetics of domain growth on liposomes consisting of a ternary mixture (unsaturated phospholipid, saturated phospholipid, and cholesterol) by temperature jump.
Bagatolli L. A. +27 more
core +3 more sources
Recent advances in mathematical modeling and statistical analysis of exocytosis in endocrine cells [PDF]
open5noMost endocrine cells secrete hormones as a result of Ca(2+)-regulated exocytosis, i.e., fusion of the membranes of hormone-containing secretory granules with the cell membrane, which allows the hormone molecules to escape to the extracellular ...
Cortese, Giuliana +4 more
core +1 more source
Membrane microdomains emergence through non-homogeneous diffusion [PDF]
In the classical view, cell membrane proteins undergo isotropic random motion, that is a 2D Brownian diffusion that should result in an homogeneous distribution of concentration. It is, however, far from the reality: Membrane proteins can assemble into so-called microdomains (sometimes called lipid rafts) which also display a specific lipid composition.
Soula, Hédi +2 more
openaire +5 more sources
A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
Activating mutations in the leucine-rich repeat kinase 2 (LRRK2) cause Parkinson’s disease, and previously we showed that activated LRRK2 phosphorylates a subset of Rab GTPases (Steger et al., 2017).
Edmundo G Vides +10 more
doaj +1 more source
Astrocytes and neurons communicate via a monocarboxylic acid shuttle [PDF]
Since formulation of the Astrocyte-Neuron Lactate Shuttle (ANLS) hypothesis in 1994, the hypothesis has provoked criticism and debate. Our review does not criticise, but rather integrates experimental data characterizing proton-linked monocarboxylate ...
Cottrell, Graeme S., Roosterman, Dirk
core +1 more source
Plasma membrane microdomains in aging and disease [PDF]
The plasma membrane of eukaryotic cells participates in signal transduction and many other cellular events to maintain the physiological state of cells. In recent decades, much attention has been paid to membrane microdomains, called lipid rafts or membrane rafts, as signaling platforms in the plasma membrane.
Yoshiko, Ohno-Iwashita +3 more
openaire +2 more sources

