Results 21 to 30 of about 232,617 (270)

Analysis of lipid-composition changes in plasma membrane microdomains[S]

open access: yesJournal of Lipid Research, 2015
Sphingolipids accumulate in plasma membrane microdomain sites, such as caveolae or lipid rafts. Such microdomains are considered to be important nexuses for signal transduction, although changes in the microdomain lipid components brought about by ...
Hideo Ogiso   +2 more
doaj   +1 more source

LPS- or Pseudomonas aeruginosa-mediated activation of the macrophage TLR4 signaling cascade depends on membrane lipid composition [PDF]

open access: yesPeerJ, 2016
It is well known that PUFA impede the LPS-mediated activation of the transcription factor NFkappaB. However, the underlying mode of action has not been clarified yet. To address this issue in a comprehensive approach, we used the monocyte/macrophage cell
Axel Schoeniger   +2 more
doaj   +2 more sources

Stepping between Membrane Microdomains [PDF]

open access: yesBiophysical Journal, 2015
Lateral membrane microdomains are postulated to be involved in a number of important functions in mammalian cells, such as membrane trafficking, exocytosis, endocytosis, signal transduction, and protein activity (1,2). These putative cell microdomains have been the subject of extensive research using a variety of biophysical and biochemical techniques,
openaire   +2 more sources

Reversible Dissolution of Microdomains in Detergent-Resistant Membranes at Physiological Temperature. [PDF]

open access: yesPLoS ONE, 2015
The formation of lipid microdomains ("rafts") is presumed to play an important role in various cellular functions, but their nature remains controversial.
Andrea Cremona   +4 more
doaj   +1 more source

Functional consequences of sphingomyelinase-induced changes in erythrocyte membrane structure. [PDF]

open access: yes, 2012
Inflammation enhances the secretion of sphingomyelinases (SMases). SMases catalyze the hydrolysis of sphingomyelin into phosphocholine and ceramide.
Bosman, GJ   +10 more
core   +1 more source

Biological and Cellular Functions of the Microdomain-Associated FWL/CNR Protein Family in Plants

open access: yesPlants, 2020
Membrane microdomains/nanodomains are sub-compartments of the plasma membrane enriched in sphingolipids and characterized by their unique protein composition.
Sandra Thibivilliers   +2 more
doaj   +1 more source

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]

open access: yes, 2016
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir   +7 more
core   +1 more source

Hydrophobically modified polyelectrolytes as potential drugs reservoirs of n-alkyl-nitroimidazoles [PDF]

open access: yes, 2007
Indexación: ScieloThe solubilization of three commercial drugs (ornindazole, metronidazole and tinidazole) and model compounds (N-alkyl-2-methyl-4-nitroimidazoles) on aggregates formed by anionic polyelectrolytes, carrying alkyl side chains of different ...
Acevedo, Betsabé   +3 more
core   +1 more source

Structure and function of the membrane microdomains in osteoclasts

open access: yesBone Research, 2023
The cell membrane structure is closely related to the occurrence and progression of many metabolic bone diseases observed in the clinic and is an important target to the development of therapeutic strategies for these diseases.
Jialong Hou   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy