Results 91 to 100 of about 34,175 (279)
Metabotropic Purinergic Receptors in Lipid Membrane Microdomains
Current Medicinal Chemistry, 2012 There is broad evidence that association of transmembrane receptors and signalling molecules with lipid rafts/caveolae provides an enriched environment for protein-protein interactions necessary for signal transduction, and a mechanism for the modulation of neurotransmitter and/or growth factor receptor function.
D' Ambrosi, N, Volonte, C
openaire +5 more sources
Membrane microdomain may be a platform for immune signaling [PDF]
Plant Signaling & Behavior, 2012 Arabidopsis RPS2 is a typical disease resistance (R) protein with nucleotide-binding leucine-rich repeats (NB-LRR). Previously, we reported that RPS2 is physically associated with some Arabidopsis hypersensitive induced reaction (AtHIR) proteins, which are enriched in membrane microdomains. Biochemical and genetic analyses suggested that members of the
Yiping, Qi, Fumiaki, Katagiri
openaire +2 more sources
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Retrovirology, 2007 Background The Nef protein of Human Immunodeficiency Viruses optimizes viral spread in the infected host by manipulating cellular transport and signal transduction machineries.
Geyer Matthias +12 more
doaj +1 more source
Membrane microdomains and cAMP compartmentation
The FASEB Journal, 2012 The role of different membrane domains in the compartmentation of cAMP signaling was investigated using the FRET‐based Epac2‐ camps biosensor. The MyrPalm sequence from Lyn kinase and the CAAX sequence from Rho GTPase were used to target this probe to lipid raft (Epac2‐MyrPalm) or non‐lipid raft (Epac2‐CAAX) membrane domains in HEK293 cells.
Shailesh Agarwal +6 more
openaire +1 more source
, 2008 Tight junctions (TJs) are specialized membrane microdomains of plasma membrane and play an important role in barrier function. IFN-gamma and TNF-alpha have been implicated in intestinal barrier dysfunction. In the present study, we analyzed the effect of
Li, Ning +20 more
core +1 more source
Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
Advanced Science, EarlyView.This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source
Insulin Resistance as a Membrane Microdomain Disorder
ChemInform, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
openaire +5 more sources
Membrane microdomains in regulation of lipid metabolism
, 2023 The fluid mosaic model described by Singer and Nicolson in 1972 was timeless and remains relevant to understanding the structure, function and dynamics of biological membranes more than fifty years later.
Veselá, Petra
core
Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays
Advanced Science, EarlyView.An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen +9 more
wiley +1 more source