Results 211 to 220 of about 29,208 (221)
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Isolation of Plasma Membrane and Plasma Membrane Microdomains
2016The plasma membrane surrounds the cytoplasm of a cell and functions as a barrier to separate the intracellular compartment from the extracellular environment. Protein and lipid components distribute nonuniformly and the components form clusters with various functions in the plasma membrane.
Anzu, Minami +3 more
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Membrane raft microdomains in chemokine receptor function
Seminars in Immunology, 2001Cell chemotaxis requires the acquisition and maintenance of both spatial and functional asymmetry between initially equivalent cell parts. In leukocytes one becomes the leading edge and the other, the rear edge or uropod. The acquisition of this cell polarity is controlled by an array of chemoattractants, including those of the chemokine family.
S, Mañes +5 more
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Functional imaging of microdomains in cell membranes
European Biophysics Journal, 2008The presence of microdomains or rafts within cell membranes is a topic of intense study and debate. The role of these structures in cell physiology, however, is also not yet fully understood with many outstanding problems. This problem is partly based on the small size of raft structures that presents significant problems to their in vivo study, i.e ...
Duggan, James +8 more
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White Matter Rafting––Membrane Microdomains in Myelin
Neurochemical Research, 2006The myelin membrane comprises a plethora of regions that are compositionally, ultrastructurally, and functionally distinct. Biochemical dissection of oligodendrocytes, Schwann cells, and central and peripheral nervous system myelin by means such as cold-detergent extraction and differential fractionation has led to the identification of a variety of ...
Lillian S, Debruin, George, Harauz
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PROTEOMICS, 2006
AbstractBiological membranes are compartmentalized into microdomains that exhibit particular lipid and protein compositions. Membrane microdomains, such as tetraspanin‐enriched microdomains and lipid rafts, have been suggested to play a role in a variety of physiological and pathological processes.
François, Le Naour +3 more
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AbstractBiological membranes are compartmentalized into microdomains that exhibit particular lipid and protein compositions. Membrane microdomains, such as tetraspanin‐enriched microdomains and lipid rafts, have been suggested to play a role in a variety of physiological and pathological processes.
François, Le Naour +3 more
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Visualization of PKA activity in plasma membrane microdomains
Mol. BioSyst., 2011Membrane rafts are sphingolipid- and cholesterol-rich microdomains that contain dynamic arrangements of signaling proteins. Notably, various components of the ubiquitous cAMP/Protein Kinase A (PKA) pathway, including β-adrenergic receptors (β-ARs), G proteins, and adenylyl cyclases (ACs), have been shown to localize differentially between membrane ...
Charlene, Depry +2 more
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Microdomains of SNARE Proteins in the Plasma Membrane
2013Exocytosis is catalyzed by the engagement of SNARE proteins embedded in the plasma membrane with complementary SNAREs in the membrane of trafficking vesicles undergoing exocytosis. In most cells studied so far, SNAREs are not randomly distributed across the plasma membrane but are clustered and segregated in discrete membrane domains of defined size ...
van den Bogaart, G., Lang, T., Jahn, R.
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Presence of detergent-resistant microdomains in lysosomal membranes
Biochemical and Biophysical Research Communications, 2002We examined the association of acetyl-CoA:alpha-glucosaminide N-acetyltransferase, a lysosomal enzyme participating in the degradation of heparan sulfate with other components of the lysosomal membrane. We prepared lysosomal membranes from human placenta and treated them with zwitterionic and non-ionic detergents.
Antje, Taute +5 more
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